| Literature DB >> 10586112 |
Abstract
This review describes the main properties of a new family of cytokine-inducible proteins which interfere with the Jak/Stat transduction pathway and negatively regulate the duration of cytokine-induced signal activation. These proteins act not only as negative feedback regulators but also inhibit response to cytokines different from those used to induce their expression. These proteins are potentially important regulators of inflammatory and immune responses of hematopoiesis and hormone response.Entities:
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Year: 1999 PMID： 10586112
Source DB: PubMed Journal: Eur Cytokine Netw ISSN： 1148-5493 Impact factor: 2.737