| Literature DB >> 10580066 |
A D Steele1, S P Parker2, I Peenze1, C T Pager1, M B Taylor3, W D Cubitt2.
Abstract
Epidemiological studies on the VP7 serotype prevalence of human rotaviruses in South Africa and the United Kingdom identified several strains which could not be serotyped as G1-G4 by monoclonal antibodies. Further analysis of these strains with a G8-specific monoclonal antibody and with probes for human rotaviruses confirmed them as G8 rotaviruses. These G8 strains exhibited a high degree of sequence identity when compared with each other and with other rotavirus G8 strains. Five South African strains were further characterized as VP6 subgroup I, but with a long RNA electropherotype, which is similar to the G8 strains previously isolated in Finland. In the UK strains, one was VP6 subgroup II with a long RNA electropherotype (similar to the Italian G8 strain). The other two were subgroup I with a short RNA electropherotype. None of these strains exhibited the super-short RNA electropherotype described in the prototype G8 strains recovered from Indonesia (69M).Entities:
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Year: 1999 PMID： 10580066 DOI： 10.1099/0022-1317-80-11-3029
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891