Literature DB >> 10579864

Cytotoxic terpenoids from the Formosan soft coral Nephthea brassica.

C Y Duh1, S K Wang, Y L Weng, M Y Chiang, C F Dai.   

Abstract

Two new cytotoxic cembranoid diterpenes, brassicolide (1) and brassicolide acetate (2); a new cytotoxic sesquiterpene, (-)-4alpha-O-acetyl-selin-11-en (3); and six cytotoxic terpenoids, (-)-selin-11-en-4alpha-ol (4), 2-hydroxynephthenol (5), nephthenol (6), cembrene A (7), epoxycembrene A (8), and (-)-beta-elemene (9), have been isolated from the Formosan soft coral Nephthea brassica. The structures of compounds 1-9 were determined by spectral, chemical, and X-ray crystallographic analysis.

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Year:  1999        PMID: 10579864     DOI: 10.1021/np990212d

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  9 in total

1.  Chemistry of the Secondary Metabolites of Termites.

Authors:  Edda Gössinger
Journal:  Prog Chem Org Nat Prod       Date:  2019

2.  New 19-oxygenated steroids from the soft coral Nephthea chabrolii.

Authors:  Shang-Kwei Wang; Shyh-Yueh Puu; Chang-Yih Duh
Journal:  Mar Drugs       Date:  2012-06-06       Impact factor: 6.085

3.  New steroids from the soft coral Nephthea chabrolii.

Authors:  Shang-Kwei Wang; Shyh-Yueh Puu; Chang-Yih Duh
Journal:  Mar Drugs       Date:  2013-02-22       Impact factor: 5.118

4.  New Anti-Inflammatory Cembranes from the Cultured Soft Coral Nephthea columnaris.

Authors:  Ting-Hsi Hsiao; Chun-Sung Sung; Yu-Hsuan Lan; Yi-Chen Wang; Mei-Chin Lu; Zhi-Hong Wen; Yang-Chang Wu; Ping-Jyun Sung
Journal:  Mar Drugs       Date:  2015-05-29       Impact factor: 5.118

5.  The anticancer effect of (1S,2S,3E,7E,11E)-3,7,11, 15-cembratetraen-17,2-olide(LS-1) through the activation of TGF-β signaling in SNU-C5/5-FU, fluorouracil-resistant human colon cancer cells.

Authors:  Eun-Ji Kim; Jung-Il Kang; Jeon-Won Kwak; Chan-Hee Jeon; Nguyen-Huu Tung; Young-Ho Kim; Cheol-Hee Choi; Jin-Won Hyun; Young-Sang Koh; Eun-Sook Yoo; Hee-Kyoung Kang
Journal:  Mar Drugs       Date:  2015-03-16       Impact factor: 5.118

6.  New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides.

Authors:  Yu-Sheng Lee; Tsai-Hui Duh; Shu-Sheng Siao; Rey-Chang Chang; Shang-Kwei Wang; Chang-Yih Duh
Journal:  Mar Drugs       Date:  2017-12-19       Impact factor: 5.118

Review 7.  Germacrene A-A Central Intermediate in Sesquiterpene Biosynthesis.

Authors:  Houchao Xu; Jeroen S Dickschat
Journal:  Chemistry       Date:  2020-09-30       Impact factor: 5.236

8.  Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China.

Authors:  Zhenliang Sun; Huiyan Wang; Jing Wang; Lianming Zhou; Peiming Yang
Journal:  PLoS One       Date:  2014-12-10       Impact factor: 3.240

Review 9.  Biological Activity of Selected Natural and Synthetic Terpenoid Lactones.

Authors:  Alicja K Surowiak; Lucyna Balcerzak; Stanisław Lochyński; Daniel J Strub
Journal:  Int J Mol Sci       Date:  2021-05-10       Impact factor: 5.923

  9 in total

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