| Literature DB >> 10567266 |
O White1, J A Eisen, J F Heidelberg, E K Hickey, J D Peterson, R J Dodson, D H Haft, M L Gwinn, W C Nelson, D L Richardson, K S Moffat, H Qin, L Jiang, W Pamphile, M Crosby, M Shen, J J Vamathevan, P Lam, L McDonald, T Utterback, C Zalewski, K S Makarova, L Aravind, M J Daly, K W Minton, R D Fleischmann, K A Ketchum, K E Nelson, S Salzberg, H O Smith, J C Venter, C M Fraser.
Abstract
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284, 156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.Entities:
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Year: 1999 PMID： 10567266 PMCID： PMC4147723 DOI： 10.1126/science.286.5444.1571
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728