Literature DB >> 10561357

Outpatient-based bone marrow transplantation for hematologic malignancies: cost saving or cost shifting?

J D Rizzo1, G B Vogelsang, S Krumm, B Frink, V Mock, E B Bass.   

Abstract

PURPOSE: To determine whether a shift in care from an inpatient-based to an outpatient-based bone marrow transplantation (BMT) program decreased charges to payers without increasing clinical complications or out-of-pocket costs to patients. PATIENTS AND METHODS: This nonrandomized prospective cohort study compared clinical and economic outcomes for 132 consecutive BMT patients with hematologic malignancies who received either inpatient- or outpatient-based BMT care.
RESULTS: Seventeen of 132 BMT patients underwent outpatient-based BMT. Compared with the inpatient-based group, the outpatient-based group had a markedly lower mean number of inpatient hospital days (22 v 47; P <.001) and decreased mean inpatient facility charges ($61,059 less per patient; P <.0001) but had higher mean outpatient facility charges ($49,732 higher; P <. 0001). Total professional fees were similar for the groups. The mean total charge to payers was only 7% less ($12,652; P =.21) for outpatient-based BMT than for inpatient-based BMT, but total charge was 34% less for outpatient compared with inpatient BMT ($54,240; P = 0.056) in a subset of patients who had a standard rather than high risk of treatment failure. There was no significant difference between groups in out-of-pocket costs for transportation, lodging, meals, home nursing, household assistance, child care, medication expenses, or unreimbursed medical bills. There also was no significant difference between groups in reported income lost, involuntary unemployment, or months of disability. The two groups had similar rates of major complications, including death, significant acute graft-versus-host disease, and veno-occlusive disease of the liver.
CONCLUSION: Increased use of outpatient-based BMT should produce substantial cost savings for payers without adverse effects on patients for those patients who do not have a high risk of treatment failure.

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Year:  1999        PMID: 10561357     DOI: 10.1200/JCO.1999.17.9.2811

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


  14 in total

1.  Costs of allogeneic hematopoietic cell transplantation with high-dose regimens.

Authors:  Akiko M Saito; Corey Cutler; David Zahrieh; Robert J Soiffer; Vincent T Ho; Edwin P Alyea; John Koreth; Joseph H Antin; Stephanie J Lee
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2.  Caregiver availability and patient access to hematopoietic cell transplantation: social worker perspectives inform practice.

Authors:  Jaime M Preussler; Lih-Wen Mau; Navneet S Majhail; Margaret Bevans; Emilie Clancy; Carolyn Messner; Leslie Parran; Kate A Pederson; Stacy Stickney Ferguson; Kent Walters; Elizabeth A Murphy; Ellen M Denzen
Journal:  Support Care Cancer       Date:  2019-03-09       Impact factor: 3.603

Review 3.  The importance of lowering the costs of stem cell transplantation in developing countries.

Authors:  Ronald D Barr
Journal:  Int J Hematol       Date:  2002-08       Impact factor: 2.490

4.  Resource Utilization and Safety of Outpatient Management Following Intensive Induction or Salvage Chemotherapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome: A Nonrandomized Clinical Comparative Analysis.

Authors:  Jennifer E Vaughn; Megan Othus; Morgan A Powell; Kelda M Gardner; Donelle L Rizzuto; Paul C Hendrie; Pamela S Becker; Paul S Pottinger; Elihu H Estey; Roland B Walter
Journal:  JAMA Oncol       Date:  2015-11       Impact factor: 31.777

5.  Costs of allogeneic hematopoietic cell transplantation using reduced intensity conditioning regimens.

Authors:  Nandita Khera; Amy Emmert; Barry E Storer; Brenda M Sandmaier; Edwin P Alyea; Stephanie J Lee
Journal:  Oncologist       Date:  2014-05-05

6.  Safety of outpatient autologous hematopoietic cell transplantation for multiple myeloma and lymphoma.

Authors:  T M Graff; A K Singavi; W Schmidt; D Eastwood; W R Drobyski; M Horowitz; J Palmer; M Pasquini; D J Rizzo; W Saber; P Hari; T S Fenske
Journal:  Bone Marrow Transplant       Date:  2015-04-13       Impact factor: 5.483

Review 7.  Costs and cost-effectiveness of hematopoietic cell transplantation.

Authors:  Jaime M Preussler; Ellen M Denzen; Navneet S Majhail
Journal:  Biol Blood Marrow Transplant       Date:  2012-04-03       Impact factor: 5.742

8.  Informal caregiving in Hematopoietic Blood and Marrow Transplant patients.

Authors:  Liz Cooke; Marcia Grant; Deborah H Eldredge; Richard T Maziarz; Lillian M Nail
Journal:  Eur J Oncol Nurs       Date:  2011-02-09       Impact factor: 2.398

Review 9.  Balancing Quality, Cost, and Access During Delivery of Newer Cellular and Immunotherapy Treatments.

Authors:  Praveen Ramakrishnan Geethakumari; Dheepthi Perumal Ramasamy; Bhagirathbhai Dholaria; Jesús Berdeja; Ankit Kansagra
Journal:  Curr Hematol Malig Rep       Date:  2021-06-05       Impact factor: 3.952

10.  Costs of autologous and allogeneic hematopoietic cell transplantation in the United States: a study using a large national private claims database.

Authors:  N S Majhail; L W Mau; E M Denzen; T J Arneson
Journal:  Bone Marrow Transplant       Date:  2012-07-09       Impact factor: 5.483

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