| Literature DB >> 1055431 |
Abstract
A diffusion model is developed to compute any moment of the sum of an arbitrary function of the gene frequency along sample paths between any two specified frequencies. This is used to calculate the mean age of a mutant of frequency chi, including or excluding the possibility of its having been at value chi equals 1 during the process, and the total frequency of heterozygotes involving an allele since its origin.Mesh:
Year: 1975 PMID: 1055431 PMCID: PMC432586 DOI: 10.1073/pnas.72.4.1602
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205