Literature DB >> 10552084

Single-photon emission tomography of a computerised model of pulmonary embolism.

J S Magnussen1, P Chicco, A W Palmer, V Bush, D W Mackey, G Storey, M Magee, G Bautovich, H Van der Wall.   

Abstract

Planar pulmonary scintigraphy is currently the standard investigation for the diagnosis of pulmonary embolism. There are a number of problems with the technique, particularly in patients with an intermediate scan report under the PIOPED criteria. The technique is also under threat from the increasing use of spiral CT angiography. A putative improvement may be gained by use of tomography. The incremental value of tomography over planar studies was therefore evaluated in a virtual model of pulmonary scintigraphy. A model of the segmental anatomy of the lungs was developed from computed tomography, cadaveric human lungs and available anatomical texts. Counts were generated within the phantom by Monte Carlo simulation of photon emission. Eighteen single segmental lesions were interspersed with 47 subsegmental defects and displayed on an Icon reporting station. These were presented in the transaxial, sagittal and coronal planes to four experienced reporters to obtain assessment of defect size. Planar studies of the same defects were displayed to the same observers in the standard eight views with a normal study for comparison. With planar studies, the accuracy of estimation of defect size was 51% compared with 97% using tomographic studies. Defects in the medial basal segment of the right lower lobe were not identified in planar studies but were easily seen by all observers in the tomographic study. It is concluded that there is marked improvement in the accuracy of determination of defect size for tomographic studies over the planar equivalents. This is especially important in the lung bases, the most common reported site of pulmonary emboli. Tomography permits visualisation of defects in the medial basal segment of the right lung, which are not seen in planar studies.

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Year:  1999        PMID: 10552084     DOI: 10.1007/s002590050475

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN: 0340-6997


  6 in total

1.  Single-photon emission computed tomography in the screening for postoperative pulmonary embolism.

Authors:  Taishi Hata; Masataka Ikeda; Shoji Nakamori; Rei Suzuki; Tonsok Kim; Masayoshi Yasui; Ichiro Takemasa; Masakazu Ikenaga; Hirofumi Yamamoto; Masayuki Ohue; Takamichi Murakami; Mitsugu Sekimoto; Masato Sakon; Morito Monden
Journal:  Dig Dis Sci       Date:  2006-09-15       Impact factor: 3.199

2.  Attenuation correction for lung SPECT: evidence of need and validation of an attenuation map derived from the emission data.

Authors:  Margarita Núñez; Vineet Prakash; Ricardo Vila; Fernando Mut; Omar Alonso; Brian F Hutton
Journal:  Eur J Nucl Med Mol Imaging       Date:  2009-02-24       Impact factor: 9.236

3.  Hyperpolarized 3He MRI and 81mKr SPECT in chronic obstructive pulmonary disease.

Authors:  Trine Stavngaard; Lise Vejby Søgaard; Jann Mortensen; Lars G Hanson; Jörg Schmiedeskamp; Anne Kiil Berthelsen; Asger Dirksen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-11-20       Impact factor: 9.236

Review 4.  Imaging of acute pulmonary embolism.

Authors:  Maria Komissarova; Suzanne Chong; Kirk Frey; Baskaran Sundaram
Journal:  Emerg Radiol       Date:  2012-11-14

5.  Assessment of regional lung functional impairment with co-registered respiratory-gated ventilation/perfusion SPET-CT images: initial experiences.

Authors:  Kazuyoshi Suga; Kawakami Yasuhiko; Mohammed Zaki; Tomio Yamashita; Aska Seto; Tsuneo Matsumoto; Naofumi Matsunaga
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-02       Impact factor: 9.236

6.  Ventilation/Perfusion SPECT for Diagnosis of Pulmonary Embolism and Other Diseases.

Authors:  Marika Bajc; Björn Jonson
Journal:  Int J Mol Imaging       Date:  2010-12-19
  6 in total

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