Literature DB >> 10551502

Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine.

K Stoeber, I Halsall, A Freeman, R Swinn, A Doble, L Morris, N Coleman, N Bullock, R A Laskey, C N Hales, G H Williams.   

Abstract

Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive immunofluorometric assay for detection of urothelial cancers based on ectopic expression of the DNA replication protein Mcm5.

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Year:  1999        PMID： 10551502     DOI： 10.1016/S0140-6736(99)04265-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  34 in total

1.  The Croonian Lecture 2001 hunting the antisocial cancer cell: MCM proteins and their exploitation.

Authors:  Ronald Laskey
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-06-29       Impact factor: 6.237

Review 2.  Replication proteins and human disease.

Authors:  Andrew P Jackson; Ronald A Laskey; Nicholas Coleman
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-01-01       Impact factor: 10.005

3.  Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-κB activation pathway and ubiquitination.

Authors:  Kah Kooi Ooi; Chien Ing Yeo; Kok-Pian Ang; Abdah Md Akim; Yoke-Kqueen Cheah; Siti Nadiah Abdul Halim; Hoi-Ling Seng; Edward R T Tiekink
Journal:  J Biol Inorg Chem       Date:  2015-05-24       Impact factor: 3.358

Review 4.  Current Use and Promise of Urinary Markers for Urothelial Cancer.

Authors:  William Tabayoyong; Ashish M Kamat
Journal:  Curr Urol Rep       Date:  2018-10-17       Impact factor: 3.092

5.  Minichromosomal Maintenance Component Complex 5 (MCM5) as a Marker of Barrett's Esophagus-Related Neoplasia: A Feasibility Study.

Authors:  M Everson; C Magee; D Alzoubaidi; S Brogden; D Graham; L B Lovat; M Novelli; R Haidry
Journal:  Dig Dis Sci       Date:  2019-04-13       Impact factor: 3.199

6.  Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts.

Authors:  Anne Sofie Brems-Eskildsen; Karsten Zieger; Helle Toldbod; Cherie Holcomb; Russell Higuchi; Francisco Mansilla; Pia P Munksgaard; Michael Borre; Torben F Ørntoft; Lars Dyrskjøt
Journal:  BMC Cancer       Date:  2010-11-24       Impact factor: 4.430

7.  DNA replication regulation protein Mcm7 as a marker of proliferation in prostate cancer.

Authors:  V Padmanabhan; P Callas; G Philips; T D Trainer; B G Beatty
Journal:  J Clin Pathol       Date:  2004-10       Impact factor: 3.411

8.  DNA replication licensing factors and aneuploidy are linked to tumor cell cycle state and clinical outcome in penile carcinoma.

Authors:  Oliver J Kayes; Marco Loddo; Nimish Patel; Pranav Patel; Suks Minhas; Gareth Ambler; Alex Freeman; Alex Wollenschlaeger; David J Ralph; Kai Stoeber; Gareth H Williams
Journal:  Clin Cancer Res       Date:  2009-11-17       Impact factor: 12.531

9.  Diagnostic and prognostic value of cell-cycle regulatory genes in malignant thyroid neoplasms.

Authors:  Electron Kebebew; Miao Peng; Emily Reiff; Quan-Yang Duh; Orlo H Clark; Alex McMillan
Journal:  World J Surg       Date:  2006-05       Impact factor: 3.352

10.  Clinical significance of MCM-2 and MCM-5 expression in colon cancer: association with clinicopathological parameters and tumor proliferative capacity.

Authors:  Constantinos Giaginis; Maria Georgiadou; Konstantina Dimakopoulou; Gerasimos Tsourouflis; Elisavet Gatzidou; Gregorios Kouraklis; Stamatios Theocharis
Journal:  Dig Dis Sci       Date:  2008-05-09       Impact factor: 3.199
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