Literature DB >> 10548748

Neuroprotective role of curcumin from curcuma longa on ethanol-induced brain damage.

V Rajakrishnan1, P Viswanathan, K N Rajasekharan, V P Menon.   

Abstract

In the present study, curcumin from Curcuma longa was screened for neuroprotective activity using ethanol as a model of brain injury. Oral administration of curcumin to rats caused a significant reversal in lipid peroxidation, brain lipids and produced enhancement of glutathione, a non-enzymic antioxidant in ethanol intoxicated rats, revealing that the antioxidative and hypolipidaemic action of curcumin is-responsible for its protective role against ethanol induced brain injury. Copyright 1999 John Wiley & Sons, Ltd.

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Year:  1999        PMID： 10548748     DOI： 10.1002/(sici)1099-1573(199911)13:7<571::aid-ptr494>3.0.co;2-7

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


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