Literature DB >> 10545986

Signaling mismatch repair in cancer.

R Fishel.   

Abstract

Clinical diagnosis of mismatch repair defects has recently been complicated by the discovery of multiple gene alterations that lead to an expanded tumor spectrum. Studies of mismatch repair protein function will improve our understanding of this process and result in better prognostic indicators of mismatch repair-associated tumor development.

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Year:  1999        PMID： 10545986     DOI： 10.1038/15191

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


  34 in total

1.  Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha.

Authors:  Xiaosheng Wu; Jeffrey L Platt; Marilia Cascalho
Journal:  Mol Cell Biol       Date:  2003-05       Impact factor: 4.272

2.  Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.

Authors:  Ruoyi Qiu; Vanessa C DeRocco; Credle Harris; Anushi Sharma; Manju M Hingorani; Dorothy A Erie; Keith R Weninger
Journal:  EMBO J       Date:  2012-04-13       Impact factor: 11.598

3.  Variation in efficiency of DNA mismatch repair at different sites in the yeast genome.

Authors:  Joshua D Hawk; Lela Stefanovic; Jayne C Boyer; Thomas D Petes; Rosann A Farber
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-02       Impact factor: 11.205

4.  ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.

Authors:  Ken-ichi Yoshioka; Yoshiko Yoshioka; Peggy Hsieh
Journal:  Mol Cell       Date:  2006-05-19       Impact factor: 17.970

5.  hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.

Authors:  Navjotsingh Pabla; Zhengwei Ma; Michael A McIlhatton; Richard Fishel; Zheng Dong
Journal:  J Biol Chem       Date:  2011-02-01       Impact factor: 5.157

6.  hMSH4-hMSH5 adenosine nucleotide processing and interactions with homologous recombination machinery.

Authors:  Timothy Snowden; Kang-Sup Shim; Christoph Schmutte; Samir Acharya; Richard Fishel
Journal:  J Biol Chem       Date:  2007-10-30       Impact factor: 5.157

7.  Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage.

Authors:  Adam S Mastrocola; Christopher D Heinen
Journal:  DNA Repair (Amst)       Date:  2009-12-08

8.  Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.

Authors:  Mindy F Reynolds; Elizabeth C Peterson-Roth; Ivan A Bespalov; Tatiana Johnston; Volkan M Gurel; Haley L Menard; Anatoly Zhitkovich
Journal:  Cancer Res       Date:  2009-01-13       Impact factor: 12.701

Review 9.  DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.

Authors:  Long Shan Li; Julio C Morales; Martina Veigl; David Sedwick; Sheldon Greer; Mark Meyers; Mark Wagner; Richard Fishel; David A Boothman
Journal:  Br J Pharmacol       Date:  2009-09-23       Impact factor: 8.739

10.  Identification of frame-shift intermediate mutant cells.

Authors:  Christoph Gasche; Christina L Chang; Loki Natarajan; Ajay Goel; Jennifer Rhees; Dennis J Young; Christian N Arnold; C Richard Boland
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-10       Impact factor: 11.205
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