Literature DB >> 10542408

How membrane proteins travel across the mitochondrial intermembrane space.

C M Koehler1, S Merchant, G Schatz.   

Abstract

A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness.

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Year:  1999        PMID： 10542408     DOI： 10.1016/s0968-0004(99)01462-0

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  39 in total

1.  Protein import channel of the outer mitochondrial membrane: a highly stable Tom40-Tom22 core structure differentially interacts with preproteins, small tom proteins, and import receptors.

Authors:  C Meisinger; M T Ryan; K Hill; K Model; J H Lim; A Sickmann; H Müller; H E Meyer; R Wagner; N Pfanner
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

2.  The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation.

Authors:  J H Lim; F Martin; B Guiard; N Pfanner; W Voos
Journal:  EMBO J       Date:  2001-03-01       Impact factor: 11.598

3.  Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence.

Authors:  A Geissler; T Krimmer; U Bömer; B Guiard; J Rassow; N Pfanner
Journal:  Mol Biol Cell       Date:  2000-11       Impact factor: 4.138

4.  The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier.

Authors:  Sean P Curran; Danielle Leuenberger; Wolfgang Oppliger; Carla M Koehler
Journal:  EMBO J       Date:  2002-03-01       Impact factor: 11.598

5.  Apocytochrome c requires the TOM complex for translocation across the mitochondrial outer membrane.

Authors:  K Diekert; A I de Kroon; U Ahting; B Niggemeyer; W Neupert; B de Kruijff; R Lill
Journal:  EMBO J       Date:  2001-10-15       Impact factor: 11.598

6.  Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria.

Authors:  D Rapaport; R D Taylor; M Käser; T Langer; W Neupert; F E Nargang
Journal:  Mol Biol Cell       Date:  2001-05       Impact factor: 4.138

Review 7.  The function of genomes in bioenergetic organelles.

Authors:  John F Allen
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2003-01-29       Impact factor: 6.237

8.  Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation.

Authors:  Samuel A Hasson; Robert Damoiseaux; Jenny D Glavin; Deepa V Dabir; Scott S Walker; Carla M Koehler
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-10       Impact factor: 11.205

9.  Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes.

Authors:  Andreja Vasiljev; Uwe Ahting; Frank E Nargang; Nancy E Go; Shukry J Habib; Christian Kozany; Valérie Panneels; Irmgard Sinning; Holger Prokisch; Walter Neupert; Stephan Nussberger; Doron Rapaport
Journal:  Mol Biol Cell       Date:  2003-12-10       Impact factor: 4.138

10.  Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import.

Authors:  Lucia Banci; Ivano Bertini; Chiara Cefaro; Lucia Cenacchi; Simone Ciofi-Baffoni; Isabella Caterina Felli; Angelo Gallo; Leonardo Gonnelli; Enrico Luchinat; Dionisia Sideris; Kostas Tokatlidis
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-08       Impact factor: 11.205
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