Literature DB >> 10539707

Inspiratory flow rates through a novel dry powder inhaler (Clickhaler) in pediatric patients with asthma.

N P Nantel1, M T Newhouse.   

Abstract

Inspiratory flow profiles through a novel dry powder inhaler (DPI) (Clickhaler; Innovata Biomed Ltd, St. Albans, UK) were recorded in 17 pediatric patients (aged 7-16 years) with stable mild to moderate asthma. Most patients (n = 14) could generate high peak inspiratory flows (PIFs) (> 60 L/min) and high flows early in the flow profile. These flows have been shown to be adequate to deaggregate and deliver micronized drug with this delivery system.

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Year:  1999        PMID: 10539707     DOI: 10.1089/jam.1999.12.55

Source DB:  PubMed          Journal:  J Aerosol Med        ISSN: 0894-2684


  3 in total

1.  Effect of rise in simulated inspiratory flow rate and carrier particle size on powder emptying from dry powder inhalers.

Authors:  V Chavan; R Dalby
Journal:  AAPS PharmSci       Date:  2000

2.  Determination of the relative bioavailability of salbutamol to the lungs following inhalation from dry powder inhaler formulations containing drug substance manufactured by supercritical fluids and micronization.

Authors:  Catherine H Richardson; Marcel de Matas; Harold Hosker; Rahul Mukherjee; Ian Wong; Henry Chrystyn
Journal:  Pharm Res       Date:  2007-05-18       Impact factor: 4.200

3.  Developing ways to evaluate in the laboratory how inhalation devices will be used by patients and care-givers: the need for clinically appropriate testing.

Authors:  Jolyon P Mitchell; Jason A Suggett
Journal:  AAPS PharmSciTech       Date:  2014-06-04       Impact factor: 3.246

  3 in total

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