Literature DB >> 10533946

Influencing antibiotic prescribing in general practice: a trial of prescriber feedback and management guidelines.

N Zwar1, J Wolk, J Gordon, R Sanson-Fisher, L Kehoe.   

Abstract

BACKGROUND: The extent of use of antibiotics to treat upper respiratory infections in general practice is an area for concern due to the increasing problem of bacterial resistance. Effective educational strategies to promote rational prescribing are needed.
OBJECTIVES: We aimed to examine the effectiveness of prescriber feedback and management guidelines in reducing antibiotics prescribing by GP trainees for undifferentiated upper respiratory tract infection, and in improving the choice of antibiotic for tonsillitis/streptococcal pharyngitis. The research tested a stepwise approach to targeting educational input to high prescribers.
METHOD: General Practice trainees in New South Wales (n = 157) were randomly allocated to a treatment group (n = 78) which received an education intervention on antibiotic use, or to a control group (n = 79) which received an intervention on an unrelated topic. Trainees completed three practice activity surveys, each of 110 consecutive patient encounters, with 6-month intervals between surveys. Prescriber feedback and management guidelines on use of antibiotics for URTI and choice of antibiotic for tonsillitis/streptococcal pharyngitis were delivered in a written form between surveys 1 and 2. An educational outreach visit to high prescribers occurred between surveys 2 and 3. Outcome measures were the rate of antibiotic prescribing for all indications, for URTI and prescribing of select antibiotics for tonsillitis/streptococcal pharyngitis.
RESULTS: Antibiotic prescribing by the intervention group declined over three occasions from 25.0 to 23.3 to 19.7 per 100 URTI problems, while the control group increased from 22.0 to 25.0 to 31.7 per 100 URTI problems (P = 0.002). Prescribing in agreement with accepted guidelines for tonsillitis/streptococcal pharyngitis increased over time in the intervention group from 55.6 to 69.8 to 73.0 per 100 problems, but decreased in the control group from 59.6 to 57.5 to 58.5 (P = 0.05).
CONCLUSION: Prescriber feedback and management guidelines were shown to influence antibiotic prescribing for URTI and choice of antibiotic for tonsillitis/streptococcal pharyngitis. This study provides a model for targeting educational input to those prescribers who most need to change their behaviour.

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Year:  1999        PMID: 10533946     DOI: 10.1093/fampra/16.5.495

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  11 in total

1.  Delayed prescriptions.

Authors:  Bruce Arroll; Tim Kenealy; Felicity Goodyear-Smith; Ngaire Kerse
Journal:  BMJ       Date:  2003-12-13

2.  Long-term effects of an educational seminar on antibiotic prescribing by GPs: a randomised controlled trial.

Authors:  Philippe Le Corvoisier; Vincent Renard; Françoise Roudot-Thoraval; Thierry Cazalens; Kalaivani Veerabudun; Florence Canoui-Poitrine; Olivier Montagne; Claude Attali
Journal:  Br J Gen Pract       Date:  2013-07       Impact factor: 5.386

3.  Optimizing fluoroquinolone utilization in a public hospital: a prospective study of educational intervention.

Authors:  K Lacombe; S Cariou; P Tilleul; G Offenstadt; J L Meynard
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2005-01       Impact factor: 3.267

Review 4.  Effectiveness of physician-targeted interventions to improve antibiotic use for respiratory tract infections.

Authors:  Alike W van der Velden; Eefje J Pijpers; Marijke M Kuyvenhoven; Sarah K G Tonkin-Crine; Paul Little; Theo J M Verheij
Journal:  Br J Gen Pract       Date:  2012-12       Impact factor: 5.386

Review 5.  Interventions to improve antibiotic prescribing practices in ambulatory care.

Authors:  S R Arnold; S E Straus
Journal:  Cochrane Database Syst Rev       Date:  2005-10-19

6.  Effectiveness of a multiple intervention to reduce antibiotic prescribing for respiratory tract symptoms in primary care: randomised controlled trial.

Authors:  Ineke Welschen; Marijke M Kuyvenhoven; Arno W Hoes; Theo J M Verheij
Journal:  BMJ       Date:  2004-08-05

Review 7.  Educational effectiveness, target, and content for prudent antibiotic use.

Authors:  Chang-Ro Lee; Jung Hun Lee; Lin-Woo Kang; Byeong Chul Jeong; Sang Hee Lee
Journal:  Biomed Res Int       Date:  2015-04-05       Impact factor: 3.411

8.  Use of behavioral economics and social psychology to improve treatment of acute respiratory infections (BEARI): rationale and design of a cluster randomized controlled trial [1RC4AG039115-01]--study protocol and baseline practice and provider characteristics.

Authors:  Stephen D Persell; Mark W Friedberg; Daniella Meeker; Jeffrey A Linder; Craig R Fox; Noah J Goldstein; Parth D Shah; Tara K Knight; Jason N Doctor
Journal:  BMC Infect Dis       Date:  2013-06-27       Impact factor: 3.090

9.  A cluster randomised controlled trial of a pharmacist-led collaborative intervention to improve statin prescribing and attainment of cholesterol targets in primary care.

Authors:  Richard Lowrie; Suzanne M Lloyd; Alex McConnachie; Jill Morrison
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

10.  Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671].

Authors:  Matthias Briel; Mirjam Christ-Crain; Jim Young; Philipp Schuetz; Peter Huber; Pierre Périat; Heiner C Bucher; Beat Müller
Journal:  BMC Fam Pract       Date:  2005-08-18       Impact factor: 2.497

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