| Literature DB >> 10530942 |
S Sardari1, Y Mori, K Horita, R G Micetich, S Nishibe, M Daneshtalab.
Abstract
Angelicin, a naturally occurring furanocoumarin, that showed antifungal activity, was considered as a lead structure for a group of synthetic coumarins. Antifungal activities of the synthesized coumarins and angelicin derivatives were reported against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae and Aspergillus niger. Human cell line cytotoxicity of several coumarins was evaluated against KB cells. Angelicin and several potent antifungals showed to be non-toxic in this assay.Entities:
Mesh:
Substances:
Year: 1999 PMID: 10530942 DOI: 10.1016/s0968-0896(99)00138-8
Source DB: PubMed Journal: Bioorg Med Chem ISSN: 0968-0896 Impact factor: 3.641