Literature DB >> 10522696

Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity.

W Lew1, P A Escarpe, D B Mendel, D J Sweeny, C U Kim.   

Abstract

The total synthesis for the determination of the absolute stereochemistry of a GS 4104 metabolite 3 is described. In addition, the influenza neuraminidase inhibitory activity of 3 and related intermediates are reported.

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Year:  1999        PMID： 10522696     DOI： 10.1016/s0960-894x(99)00479-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Enhanced taxonomy annotation of antiviral activity data from ChEMBL.

Authors:  Anastasia A Nikitina; Alexey A Orlov; Liubov I Kozlovskaya; Vladimir A Palyulin; Dmitry I Osolodkin
Journal:  Database (Oxford)       Date:  2019-01-01       Impact factor: 3.451

Review 2.  Anti-influenza virus agents: synthesis and mode of action.

Authors:  Irene M Lagoja; Erik De Clercq
Journal:  Med Res Rev       Date:  2008-01       Impact factor: 12.944

Review 3.  Recent Advances in the Synthesis of Polyamine Derivatives and Their Applications.

Authors:  Artemiy Nichugovskiy; Gian Cesare Tron; Mikhail Maslov
Journal:  Molecules       Date:  2021-10-30       Impact factor: 4.411
  3 in total

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