Literature DB >> 10521423

Characterization of an 8-oxoguanine DNA glycosylase from Methanococcus jannaschii.

A Gogos1, N D Clarke.   

Abstract

A thermostable 8-oxoguanine (oxoG) DNA glycosylase from Methanococcus jannaschii has been expressed in Escherichia coli, purified, and characterized. The enzyme, which has been named mjOgg, belongs to the same diverse DNA glycosylase superfamily as the 8-oxoguanine DNA glycosylases from yeast (yOgg1) and human (hOgg1) but is substantially different in sequence. In addition, unlike its eukaryotic counterparts, which have a strong preference for oxoG.C base pairs, mjOgg has little specificity for the base opposite oxoG. mjOgg has both DNA glycosylase and DNA lyase (beta-elimination) activity, and the combined glycosylase/lyase activity occurs at a rate comparable with the glycosylase activity alone. Mutation of Lys-129, analogous to Lys-241 of yOgg1, abolishes glycosylase activity.

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Year:  1999        PMID： 10521423     DOI： 10.1074/jbc.274.43.30447

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  9 in total

1.  Repair of oxidative DNA damage in Drosophila melanogaster: identification and characterization of dOgg1, a second DNA glycosylase activity for 8-hydroxyguanine and formamidopyrimidines.

Authors:  C Dherin; M Dizdaroglu; H Doerflinger; S Boiteux; J P Radicella
Journal:  Nucleic Acids Res       Date:  2000-12-01       Impact factor: 16.971

Review 2.  Recent advances in the structural mechanisms of DNA glycosylases.

Authors:  Sonja C Brooks; Suraj Adhikary; Emily H Rubinson; Brandt F Eichman
Journal:  Biochim Biophys Acta       Date:  2012-10-14

3.  The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.

Authors:  Kim Brügger; Lanming Chen; Markus Stark; Arne Zibat; Peter Redder; Andreas Ruepp; Mariana Awayez; Qunxin She; Roger A Garrett; Hans-Peter Klenk
Journal:  Archaea       Date:  2007-05       Impact factor: 3.273

4.  The C-terminal lysine of Ogg2 DNA glycosylases is a major molecular determinant for guanine/8-oxoguanine distinction.

Authors:  Frédérick Faucher; Susan S Wallace; Sylvie Doublié
Journal:  J Mol Biol       Date:  2010-01-18       Impact factor: 5.469

5.  Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction.

Authors:  Frédérick Faucher; Stéphanie Duclos; Viswanath Bandaru; Susan S Wallace; Sylvie Doublié
Journal:  Structure       Date:  2009-05-13       Impact factor: 5.006

6.  Clostridium acetobutylicum 8-oxoguanine DNA glycosylase (Ogg) differs from eukaryotic Oggs with respect to opposite base discrimination.

Authors:  Susan M Robey-Bond; Ramiro Barrantes-Reynolds; Jeffrey P Bond; Susan S Wallace; Viswanath Bandaru
Journal:  Biochemistry       Date:  2008-06-26       Impact factor: 3.162

7.  Structural characterization of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase in its apo form and in complex with 8-oxodeoxyguanosine.

Authors:  Frédérick Faucher; Susan M Robey-Bond; Susan S Wallace; Sylvie Doublié
Journal:  J Mol Biol       Date:  2009-02-09       Impact factor: 5.469

8.  Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase.

Authors:  Frédérick Faucher; Susan S Wallace; Sylvie Doublié
Journal:  DNA Repair (Amst)       Date:  2009-09-10

Review 9.  8-oxoguanine DNA glycosylases: one lesion, three subfamilies.

Authors:  Frédérick Faucher; Sylvie Doublié; Zongchao Jia
Journal:  Int J Mol Sci       Date:  2012-06-01       Impact factor: 6.208
  9 in total

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