Literature DB >> 10518090

Lower esophageal sphincter position in premature infants cannot be correctly estimated with current formulas.

T I Omari1, M A Benninga, R R Haslam, C P Barnett, G P Davidson, J Dent.   

Abstract

OBJECTIVES: Strobel's formula (Esophageal length = 5 + 0.252 x Height) is frequently used as a guide for determining the distance from the nares to the lower esophageal sphincter (LES) in term infants. The aim of this study was to examine this relationship in premature infants. STUDY
DESIGN: The distance from nares to LES was manometrically determined in 156 premature infants (26-40 weeks' postmenstrual age; body weights of 610-3050 g). The ability of body weight, height (body length), head circumference, and postmenstrual age to predict the manometrically determined LES position was evaluated with linear and non-linear regression analyses.
RESULTS: Body weight and body length were the most predictive of distance from nares to LES (r(2) = 0.848 and 0.802, respectively). These relationships were non-linear and, in the case of body length, deviated substantially from Strobel's model.
CONCLUSIONS: In premature neonates, a different formula is needed for prediction of the distance between nares and LES than that applied to term infants and children.

Entities:  

Mesh:

Year:  1999        PMID: 10518090     DOI: 10.1016/s0022-3476(99)70179-4

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  6 in total

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2.  Multipoint measurement of intragastric pH in healthy preterm infants.

Authors:  T I Omari; G P Davidson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2003-11       Impact factor: 5.747

3.  The relationship between somatic growth and in vivo esophageal segmental and sphincteric growth in human neonates.

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4.  Effects of Esophageal Acidification on Troublesome Symptoms: An Approach to Characterize True Acid GERD in Dysphagic Neonates.

Authors:  Maneesha Sivalingam; Swetha Sitaram; Kathryn A Hasenstab; Lai Wei; Frederick W Woodley; Sudarshan R Jadcherla
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5.  Pharmacodynamics and safety of pantoprazole in neonates, preterm infants, and infants aged 1 through 11 months with a clinical diagnosis of gastroesophageal reflux disease.

Authors:  Jaroslaw Kierkus; Wanda Furmaga-Jablonska; Janice E Sullivan; Elmer S David; Dan L Stewart; Natalie Rath; Caifeng Fu; Wenjin Wang; Mary K Maguire; Gail M Comer
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6.  Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease.

Authors:  T I Omari; C P Barnett; M A Benninga; R Lontis; L Goodchild; R R Haslam; J Dent; G P Davidson
Journal:  Gut       Date:  2002-10       Impact factor: 23.059

  6 in total

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