Literature DB >> 10517523

A comparative study on viscosity of human, bovine and pig IgG immunoglobulins in aqueous solutions.

K Monkos1, B Turczynski.   

Abstract

This paper presents the results of viscosity determinations on aqueous solutions of human, bovine and pig IgG immunoglobulins over a wide range of concentrations and at temperatures ranging from 5 degrees C to 55 degrees C. On the basis of the generalized Arrhenius formula, the viscosity temperature and the viscosity concentration dependence of the solutions are discussed. By applying an asymptotic form of the generalized Arrhenius formula, such rheological quantities as the intrinsic viscosity and Huggins coefficient were calculated.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10517523     DOI: 10.1016/s0141-8130(99)00080-x

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  7 in total

1.  Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association.

Authors:  Muppalla Sukumar; Brandon L Doyle; Jessica L Combs; Allen H Pekar
Journal:  Pharm Res       Date:  2004-07       Impact factor: 4.200

2.  Challenges in Determining Intrinsic Viscosity Under Low Ionic Strength Solution Conditions.

Authors:  Mariya A Pindrus; Steven J Shire; Sandeep Yadav; Devendra S Kalonia
Journal:  Pharm Res       Date:  2017-02-02       Impact factor: 4.200

3.  Determination of some hydrodynamic parameters of ovine serum albumin solutions using viscometric measurements.

Authors:  Karol Monkos
Journal:  J Biol Phys       Date:  2005-05       Impact factor: 1.365

4.  Effect of sugar molecules on the viscosity of high concentration monoclonal antibody solutions.

Authors:  Feng He; Christopher E Woods; Jennifer R Litowski; Lauren A Roschen; Himanshu S Gadgil; Vladimir I Razinkov; Bruce A Kerwin
Journal:  Pharm Res       Date:  2011-05-15       Impact factor: 4.200

5.  Systematic interpolation method predicts protein chromatographic elution from batch isotherm data without a detailed mechanistic isotherm model.

Authors:  Arch Creasy; Gregory Barker; Yan Yao; Giorgio Carta
Journal:  Biotechnol J       Date:  2015-06-24       Impact factor: 4.677

6.  Multi-criteria manufacturability indices for ranking high-concentration monoclonal antibody formulations.

Authors:  Yang Yang; Ajoy Velayudhan; Nina F Thornhill; Suzanne S Farid
Journal:  Biotechnol Bioeng       Date:  2017-05-26       Impact factor: 4.530

Review 7.  Viscosity Control of Protein Solution by Small Solutes: A Review.

Authors:  Taehun Hong; Kazuki Iwashita; Kentaro Shiraki
Journal:  Curr Protein Pept Sci       Date:  2018       Impact factor: 3.272

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.