| Literature DB >> 10514105 |
J Ojaimi1, C L Masters, C McLean, K Opeskin, P McKelvie, E Byrne.
Abstract
This study aims to investigate the cellular distribution of human cytochrome c oxidase (COX) subunit II (CII) and COX subunit IV (CIV) in Alzheimer's disease relative to control brains. The levels of CIV and CII proteins in the cerebellar Purkinje cells were reduced in age-matched controls relative to young controls and in the Alzheimer's disease group relative to both age-matched and young controls. Results suggest that these age-associated changes are more marked in Alzheimer's disease.Entities:
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Year: 1999 PMID： 10514105
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422