F Benazzi1. 1. Department of Psychiatry, Public Hospital Morgagni, Forlì, Italy. f.benazzi@fo.nettuno.it
Abstract
BACKGROUND: The relationship between bipolar and unipolar psychotic depression has not been well studied. Therefore, the aim of the present study was to compare bipolar with unipolar psychotic outpatient depression. METHODS: Seventy consecutive unipolar (n = 40) and bipolar (n = 30) psychotic depressed outpatients were interviewed with the Structured Clinical Interview for DSM-IV, the Montgomery Asberg Depression Rating Scale, the Global Assessment of Functioning Scale, and the Brief Psychiatric Rating Scale. RESULTS: Of the variables studied (age, duration of illness, severity, recurrences, atypical features, chronicity, gender, comorbidity, hallucinations, delusions), none was significantly different between unipolar and bipolar psychotic patients. CONCLUSIONS: Bipolar psychotic depression was similar to unipolar psychotic depression on variables reported in the literature to distinguish bipolar from unipolar disorder. CLINICAL IMPLICATIONS: The findings might suggest, but do not necessarily imply, that psychotic depression might be a distinct clinical entity. LIMITATIONS: Single interviewer, nonblind cross-sectional assessment, outpatient sample, sample size.
BACKGROUND: The relationship between bipolar and unipolar psychotic depression has not been well studied. Therefore, the aim of the present study was to compare bipolar with unipolar psychoticoutpatientdepression. METHODS: Seventy consecutive unipolar (n = 40) and bipolar (n = 30) psychotic depressed outpatients were interviewed with the Structured Clinical Interview for DSM-IV, the Montgomery Asberg Depression Rating Scale, the Global Assessment of Functioning Scale, and the Brief Psychiatric Rating Scale. RESULTS: Of the variables studied (age, duration of illness, severity, recurrences, atypical features, chronicity, gender, comorbidity, hallucinations, delusions), none was significantly different between unipolar and bipolar psychoticpatients. CONCLUSIONS:Bipolar psychotic depression was similar to unipolar psychotic depression on variables reported in the literature to distinguish bipolar from unipolar disorder. CLINICAL IMPLICATIONS: The findings might suggest, but do not necessarily imply, that psychotic depression might be a distinct clinical entity. LIMITATIONS: Single interviewer, nonblind cross-sectional assessment, outpatient sample, sample size.
Authors: Carmen Moreno; Deborah S Hasin; Celso Arango; Maria A Oquendo; Eduard Vieta; Shangmin Liu; Bridget F Grant; Carlos Blanco Journal: Bipolar Disord Date: 2012-05 Impact factor: 6.744
Authors: S D Østergaard; A J Rothschild; A J Flint; B H Mulsant; E M Whyte; A K Leadholm; P Bech; B S Meyers Journal: Acta Psychiatr Scand Date: 2015-05-27 Impact factor: 6.392