F Benazzi1. 1. Department of Psychiatry, Morgagni Public Hospital, Forlì, Italy. f.benazzi@fo.nettuno.it
Abstract
OBJECTIVE: To compare the clinical features and the outcome between patients with early- and late-onset bipolar II disorder. DESIGN: Case series. SETTING: Outpatient private practice. PATIENTS: One hundred and seventy-nine consecutive outpatients with bipolar II disorder presenting for treatment of a major depressive episode. OUTCOME MEASURES: Duration of illness, severity of depression, recurrences, psychosis, chronicity, atypical features and comorbidity. RESULTS: Patients with early-onset (before 20, 25 or 30 years of age) bipolar II disorder had a significantly longer duration of illness and more recurrences compared with patients with late-onset (after 20, 25 or 30 years of age) bipolar II disorder. All other variables were not significantly different between the 2 groups. CONCLUSIONS: Indicators of worse outcome (severity of depression, psychosis, chronicity, comorbidity) were not significantly different between patients with early- and late-onset bipolar II disorder.
OBJECTIVE: To compare the clinical features and the outcome between patients with early- and late-onset bipolar II disorder. DESIGN: Case series. SETTING:Outpatient private practice. PATIENTS: One hundred and seventy-nine consecutive outpatients with bipolar II disorder presenting for treatment of a major depressive episode. OUTCOME MEASURES: Duration of illness, severity of depression, recurrences, psychosis, chronicity, atypical features and comorbidity. RESULTS:Patients with early-onset (before 20, 25 or 30 years of age) bipolar II disorder had a significantly longer duration of illness and more recurrences compared with patients with late-onset (after 20, 25 or 30 years of age) bipolar II disorder. All other variables were not significantly different between the 2 groups. CONCLUSIONS: Indicators of worse outcome (severity of depression, psychosis, chronicity, comorbidity) were not significantly different between patients with early- and late-onset bipolar II disorder.
Authors: I Elkin; M T Shea; J T Watkins; S D Imber; S M Sotsky; J F Collins; D R Glass; P A Pilkonis; W R Leber; J P Docherty Journal: Arch Gen Psychiatry Date: 1989-11
Authors: E S Gershon; J Hamovit; J J Guroff; E Dibble; J F Leckman; W Sceery; S D Targum; J I Nurnberger; L R Goldin; W E Bunney Journal: Arch Gen Psychiatry Date: 1982-10
Authors: J Rice; T Reich; N C Andreasen; J Endicott; M Van Eerdewegh; R Fishman; R M Hirschfeld; G L Klerman Journal: Arch Gen Psychiatry Date: 1987-05