Literature DB >> 10498213

Isoquinoline-6-carboxamides as potent and selective anti-human cytomegalovirus (HCMV) inhibitors.

L Chan1, H Jin, T Stefanac, W Wang, J F Lavallée, J Bédard, S May.   

Abstract

Structure-activity relationship studies on our newly identified anti-HCMV compounds, the 1,6-naphthyridines led to the identification of isoquinoline-6-carboxamides as potent and selective anti-HCMV agents.

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Year:  1999        PMID： 10498213     DOI： 10.1016/s0960-894x(99)00435-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

Review 1.  Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.

Authors:  Shikha Kumari; Angelica V Carmona; Amit K Tiwari; Paul C Trippier
Journal:  J Med Chem       Date:  2020-08-04       Impact factor: 7.446

2.  Antiviral properties of a series of 1,6-naphthyridine and 7, 8-dihydroisoquinoline derivatives exhibiting potent activity against human cytomegalovirus.

Authors:  J Bedard; S May; L L'Heureux; T Stamminger; A Copsey; J Drach; J Huffman; L Chan; H Jin; R F Rando
Journal:  Antimicrob Agents Chemother       Date:  2000-04       Impact factor: 5.191

3.  Investigating the spectrum of biological activity of substituted quinoline-2-carboxamides and their isosteres.

Authors:  Tomas Gonec; Pavel Bobal; Josef Sujan; Matus Pesko; Jiahui Guo; Katarina Kralova; Lenka Pavlacka; Libor Vesely; Eva Kreckova; Jiri Kos; Aidan Coffey; Peter Kollar; Ales Imramovsky; Lukas Placek; Josef Jampilek
Journal:  Molecules       Date:  2012-01-10       Impact factor: 4.411

4.  Microwave-assisted synthesis of new substituted anilides of quinaldic acid.

Authors:  Pavel Bobal; Josef Sujan; Jan Otevrel; Ales Imramovsky; Zdenka Padelkova; Josef Jampilek
Journal:  Molecules       Date:  2012-01-31       Impact factor: 4.411
  4 in total

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