Literature DB >> 10493714

Applying research evidence to individuals in primary care: a study using non-rheumatic atrial fibrillation.

N Oswald1, H Bateman.   

Abstract

BACKGROUND: There is strong research evidence that anticoagulation of patients with nonrheumatic atrial fibrillation reduces the morbidity and mortality of stroke. This evidence is incompletely applied.
OBJECTIVES: We aimed to report consequences associated with the intention to apply evidence about anticoagulation for non-rheumatic atrial fibrillation (NRAF) to individuals in general medical practice.
METHODS: The study involved prospective structured reporting of the processes of applying evidence about NRAF to individual patients in six general practices in Cambridge. The subjects were patients identified to have NRAF in these practices. The intervention consisted of a practice-based review of evidence and the construction of a practice-owned protocol. This was followed by a review of individual patients' records according to protocol criteria. The main outcomes were indentification of the characteristics of the patients, quantitation of GPs' intention to change treatment, explicit reporting of the reasons for not anticoagulating individuals and time to achieve the practice protocol.
RESULTS: The data collected confirmed that patients excluded from the authoritative randomized controlled trials predominate among patients cared for in general medical practice. Practitioners overestimated the prevalence of NRAF in their patients and underestimated the extent to which their current practice offered intervention. Practitioners initially overestimated the amount of change required in patient management. In reviewing their patients' records with the intention of following evidence-based practice, practitioners explicitly described and regarded as appropriate their reasons for not prescribing anticoagulation to certain individuals. The review process was time-consuming and will need to be repeated as further evidence emerges.

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Year:  1999        PMID: 10493714     DOI: 10.1093/fampra/16.4.414

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  9 in total

1.  Anticoagulation to prevent stroke in atrial fibrillation. It's still not clear whether results in secondary care translate to primary care.

Authors:  D A Fitzmaurice; J Mant; E T Murray; F D Hobbs
Journal:  BMJ       Date:  2000-11-04

Review 2.  Case report of paroxysmal atrial fibrillation and anticoagulation.

Authors:  Shmuel Reis; Doron Hermoni; Pnina Livingstone; Jeffrey Borkan
Journal:  BMJ       Date:  2002-11-02

3.  Evaluating factors affecting the implementation of evidence based medicine in primary healthcare centers in Dubai.

Authors:  Ahmed I Albarrak; Suhair Aqil Ali Abbdulrahim; Rafiuddin Mohammed
Journal:  Saudi Pharm J       Date:  2013-05-30       Impact factor: 4.330

4.  Does the evidence referenced in NICE guidelines reflect a primary care population?

Authors:  Paul Scullard; Asmaa Abdelhamid; Nick Steel; Nadeem Qureshi
Journal:  Br J Gen Pract       Date:  2011-03       Impact factor: 5.386

5.  Anticoagulation in atrial fibrillation. Is there a gap in care for ambulatory patients?

Authors:  Wayne Putnam; Kelly Nicol; David Anderson; Brenda Brownell; Meredith Chiasson; Frederick I Burge; Gordon Flowerdew; Jafna Cox
Journal:  Can Fam Physician       Date:  2004-09       Impact factor: 3.275

6.  Are guidelines ethical? Some considerations for general practice.

Authors:  Wendy A Rogers
Journal:  Br J Gen Pract       Date:  2002-08       Impact factor: 5.386

7.  Is there a tension between doctors' duty of care and evidence-based medicine?

Authors:  Wendy A Rogers
Journal:  Health Care Anal       Date:  2002

8.  Implementing evidence-based medicine in general practice: a focus group based study.

Authors:  Karin Hannes; Marcus Leys; Etienne Vermeire; Bert Aertgeerts; Frank Buntinx; Anne-Marie Depoorter
Journal:  BMC Fam Pract       Date:  2005-09-09       Impact factor: 2.497

Review 9.  Clinical and economic burden of adverse drug reactions.

Authors:  Janet Sultana; Paola Cutroneo; Gianluca Trifirò
Journal:  J Pharmacol Pharmacother       Date:  2013-12
  9 in total

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