Literature DB >> 104936

Is GIP a glucagon cell constituent?

J Alumets, R Håkanson, T O'Dorisio, K Sjölund, F Sundler.   

Abstract

"Gastric inhibitory peptide" or "glucose-dependent insulin-releasing peptide" (GIP) is a member of the gut hormone family. Its physiological action is thought to be related to its insulinotrophic effect. The occurrence and distribution of GIP was studied by immunohistochemistry. In all species examined including man, GIP immunoreactivity was found to reside in the glucagon cells of the pancrease and gut. Three pancreatic glucagonomas were found to contain numerous cells displaying GIP and glucagon immunoreactivity. The GIP antiserum used did not cross react with either pancreatic-type or gut-type glucagon (GLI).

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Year:  1978        PMID： 104936     DOI： 10.1007/bf00495381

Source DB:  PubMed          Journal:  Histochemistry        ISSN： 0301-5564


  9 in total

1.  Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study.

Authors:  L I Larsson; J Holst; R Håkanson; F Sundler
Journal:  Histochemistry       Date:  1975-09-29

Review 2.  Identification and actions of gastric inhibitory polypeptide.

Authors:  J C Brown; J R Dryburgh; S A Ross; J Dupré
Journal:  Recent Prog Horm Res       Date:  1975

3.  Immunocytochemical localization of a gastric imhibitory polypeptide-like material within A-cells of the endocrine pancreas.

Authors:  P H Smith; F W Merchant; D G Johnson; W Y Fujimoto; R H Williams
Journal:  Am J Anat       Date:  1977-08

4.  Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum.

Authors:  J M Polak; S R Bloom; M Kuzio; J C Brown; A G Pearse
Journal:  Gut       Date:  1973-04       Impact factor: 23.059

5.  Candidate hormones of the gut. I. Introduction.

Authors:  M I Grossman
Journal:  Gastroenterology       Date:  1974-10       Impact factor: 22.682

6.  Diethylpyrocarbonate, a vapour-phase fixative for immunofluorescence studies on polypeptide hormones.

Authors:  A G Pearse; J M Polak; C Adams; P A Kendall
Journal:  Histochem J       Date:  1974-05

7.  Further purification of a polypeptide demonstrating enterogastrone activity.

Authors:  J C Brown; V Mutt; R A Pederson
Journal:  J Physiol       Date:  1970-07       Impact factor: 5.182

8.  Gastric inhibitory polypeptide (GIP). Intestinal distribution and stimulation by amino acids and medium-chain triglycerides.

Authors:  T M O'Dorisio; S Cataland; M Stevenson; E L Mazzaferri
Journal:  Am J Dig Dis       Date:  1976-09

9.  Electronimmunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man.

Authors:  A M Buchan; J M Polak; C Capella; E Solcia; A G Pearse
Journal:  Histochemistry       Date:  1978-06-02
  9 in total
  13 in total

1.  Detection of glucagon in pancreatic A-cells by monoclonal antibodies.

Authors:  J Metz; B Ruschemeier; G Moldenhauer
Journal:  Histochemistry       Date:  1985

2.  An immunocytochemical study of endocrine pancreas of snakes.

Authors:  A M Buchan
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

3.  Immunohistochemical identification of factor X-like antigen in the A cells of the normal human pancreas.

Authors:  C Betterle; A Trevisan; A Girolami
Journal:  Diabetologia       Date:  1982-09       Impact factor: 10.122

4.  Immunoreactivities of gastrin (G-) cells. II. Non-specific binding of immunoglobulins to G-cells by ionic interactions.

Authors:  D Grube
Journal:  Histochemistry       Date:  1980

Review 5.  Update on prevalence and distribution pattern of tick-borne diseases among humans in India: a review.

Authors:  Tripti Negi; Laxman Singh Kandari; Kusum Arunachalam
Journal:  Parasitol Res       Date:  2021-04-02       Impact factor: 2.289

Review 6.  Clinical aspects of GIP secretion.

Authors:  B Beck; C Villaume; G Debry
Journal:  Acta Diabetol Lat       Date:  1982 Jan-Mar

7.  Ultrastructural localization of secretin in endocrine cells of the dog duodenum by the immunogold technique. Comparison with ultrastructurally characterized S cells of various mammals.

Authors:  L Usellini; C Capella; B Frigerio; G Rindi; E Solcia
Journal:  Histochemistry       Date:  1984

8.  Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa.

Authors:  L Usellini; C Capella; E Solcia; A M Buchan; J C Brown
Journal:  Histochemistry       Date:  1984

9.  Duodenal endocrine cells in adult coeliac disease.

Authors:  K Sjölund; J Alumets; N O Berg; R Håkanson; F Sundler
Journal:  Gut       Date:  1979-07       Impact factor: 23.059

10.  A comparison of the ability of serum and monoclonal antibodies to gastric inhibitory polypeptide to detect immunoreactive cells in the gastroenteropancreatic system of mammals and reptiles.

Authors:  A M Buchan; J Ingman-Baker; J Levy; J C Brown
Journal:  Histochemistry       Date:  1982
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