STUDY OBJECTIVES: To identify pulmonary risk factors associated with prolonged ICU stay in young children (< or = 2 years) undergoing surgical repair for congenital heart disease (CHD). DESIGN: Retrospective case series analysis. SETTING: Tertiary-care facility. PATIENTS: Clinical records of 134 consecutive patients aged < or = 2 years undergoing cardiac surgery for CHD were reviewed, and 37 were excluded according to inclusion criteria. Thus, 97 patients were allocated to two groups based on the duration of ICU stay: < or = 7 days (group 1, n = 57), and > 7 days (group 2, n = 40). RESULTS: Mean ICU duration for groups 1 and 2 was 3.0 +/- 0.4 days and 28.1 +/- 4.4 days, respectively (p < 0.001). In group 1, there were three extubation failures, whereas 41 extubation failures occurred in group 2 (p < 0.0001). A total of 22 patients (4 in group 1 and 18 in group 2) developed noninfectious pulmonary complications, such as airway problems, including extrinsic airway compression and tracheobronchomalacia (n = 6); pulmonary hypertension (n = 5); phrenic nerve palsy (n = 7); and pleural effusion (n = 8). These 22 patients (23%) contributed to the majority of total ventilator days (67%) as well as ICU stay (61%). CONCLUSIONS: Pulmonary complications in general, and central airway problems in particular, are a frequent cause for delayed recovery following cardiac surgery in young children.
STUDY OBJECTIVES: To identify pulmonary risk factors associated with prolonged ICU stay in young children (< or = 2 years) undergoing surgical repair for congenital heart disease (CHD). DESIGN: Retrospective case series analysis. SETTING: Tertiary-care facility. PATIENTS: Clinical records of 134 consecutive patients aged < or = 2 years undergoing cardiac surgery for CHD were reviewed, and 37 were excluded according to inclusion criteria. Thus, 97 patients were allocated to two groups based on the duration of ICU stay: < or = 7 days (group 1, n = 57), and > 7 days (group 2, n = 40). RESULTS: Mean ICU duration for groups 1 and 2 was 3.0 +/- 0.4 days and 28.1 +/- 4.4 days, respectively (p < 0.001). In group 1, there were three extubation failures, whereas 41 extubation failures occurred in group 2 (p < 0.0001). A total of 22 patients (4 in group 1 and 18 in group 2) developed noninfectious pulmonary complications, such as airway problems, including extrinsic airway compression and tracheobronchomalacia (n = 6); pulmonary hypertension (n = 5); phrenic nerve palsy (n = 7); and pleural effusion (n = 8). These 22 patients (23%) contributed to the majority of total ventilator days (67%) as well as ICU stay (61%). CONCLUSIONS: Pulmonary complications in general, and central airway problems in particular, are a frequent cause for delayed recovery following cardiac surgery in young children.
Authors: Jeffrey A Canter; Marshall L Summar; Heidi B Smith; Geraldine D Rice; Lynn D Hall; Marylyn D Ritchie; Alison A Motsinger; Karla G Christian; Davis C Drinkwater; Frank G Scholl; Karrie L Dyer; Ann L Kavanaugh-McHugh; Frederick E Barr Journal: Mitochondrion Date: 2006-11-29 Impact factor: 4.160
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Authors: Jodi Chen; Robert A Zimmerman; Gail P Jarvik; Alex S Nord; Robert R Clancy; Gil Wernovsky; Lisa M Montenegro; Diane M Hartman; Susan C Nicolson; Thomas L Spray; J William Gaynor; Rebecca Ichord Journal: Ann Thorac Surg Date: 2009-09 Impact factor: 4.330
Authors: Michael Gaies; David K Werho; Wenying Zhang; Janet E Donohue; Sarah Tabbutt; Nancy S Ghanayem; Mark A Scheurer; John M Costello; J William Gaynor; Sara K Pasquali; Justin B Dimick; Mousumi Banerjee; Steven M Schwartz Journal: Ann Thorac Surg Date: 2017-10-05 Impact factor: 4.330