Literature DB >> 10486362

Restorative proctocolectomy for distal ulcerative colitis.

M Brunel1, C Penna, E Tiret, P Balladur, R Parc.   

Abstract

BACKGROUND: Chronic distal colitis may cause troublesome symptoms and alter quality of life. When medical treatment fails to control symptoms, patients and doctors are often reluctant to consider surgical resection because of the relatively small portion of the large bowel affected by the disease. AIM: To assess the outcome of restorative proctocolectomy (RP) in patients with distal colitis who required surgery for chronic debilitating symptoms and failed medical management. PATIENTS/
METHODS: From 1986 to 1996, of 263 patients receiving RP for ulcerative colitis, 27 (16 men) were operated on for distal ulcerative colitis limited to the rectum and sigmoid colon. Bowel function and quality of life were compared before and one year after RP.
RESULTS: The mean (SD) duration of ulcerative colitis was 11 (6) years. RP was performed at a mean age of 46 (10) years. All the pouches were J-shaped, and a diverting loop ileostomy was always performed. Mean (SD) hospital stay was 25 (10) days. Seven complications occurred in six patients. Previously unknown severe dysplasia was discovered on the colectomy specimen in two patients. After RP there was a significant decrease in mean (SD) daytime stool frequency (8.2 (4) v 4.7 (2), p<0.05), night-time stool frequency (2 (2) v 1 (1), p = 0.05), and the number of patients with urgency to defecate (26/27 v 1/27, p<0.001). Sex life was improved in eight patients, social life in 26, and professional life in eight. Twenty six patients were satisfied with the results, and 25 wished that they had received surgery earlier in the course of their disease.
CONCLUSION: RP can improve bowel function and quality of life in patients with disabling chronic symptoms of distal ulcerative colitis.

Entities:  

Mesh:

Year:  1999        PMID: 10486362      PMCID: PMC1727695          DOI: 10.1136/gut.45.4.542

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  10 in total

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Journal:  Scand J Gastroenterol Suppl       Date:  1992

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3.  Quality of life after Brooke ileostomy and ileal pouch-anal anastomosis. Comparison of performance status.

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Journal:  Scand J Gastroenterol Suppl       Date:  1983

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Journal:  Gut       Date:  1996-04       Impact factor: 23.059

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9.  Ileal pouch-anal anastomoses complications and function in 1005 patients.

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Journal:  Ann Surg       Date:  1995-08       Impact factor: 12.969

10.  Quality of life after restorative proctocolectomy with a pelvic ileal reservoir compares favorably with that of patients with medically treated colitis.

Authors:  P M Sagar; W Lewis; P J Holdsworth; D Johnston; C Mitchell; J MacFie
Journal:  Dis Colon Rectum       Date:  1993-06       Impact factor: 4.585

  10 in total
  4 in total

1.  Recent advances in the management of distal ulcerative colitis.

Authors:  Ioannis E Koutroubakis
Journal:  World J Gastrointest Pharmacol Ther       Date:  2010-04-06

2.  Ileal lesions in patients with ulcerative colitis after ileo-rectal anastomosis: relationship with colonic metaplasia.

Authors:  Livia Biancone; Emma Calabrese; Giampiero Palmieri; Carmelina Petruzziello; Sara Onali; Giuseppe-Sigismondo Sica; Marta Cossignani; Giovanna Condino; Kiron-Moy Das; Francesco Pallone
Journal:  World J Gastroenterol       Date:  2008-09-14       Impact factor: 5.742

3.  Outcome of patients undergoing ileal pouch-anal anastomosis for left-sided chronic ulcerative colitis.

Authors:  I Hassan; A F Horgan; S Nivatvongs; J Harrington; D R Larson
Journal:  J Gastrointest Surg       Date:  2003 May-Jun       Impact factor: 3.452

Review 4.  When disease extent is not always a key parameter: Management of refractory ulcerative proctitis.

Authors:  Georgios Michalopoulos; Konstantinos Karmiris
Journal:  Curr Res Pharmacol Drug Discov       Date:  2021-12-11
  4 in total

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