Literature DB >> 10482863

Update on therapy of atopic dermatitis.

J M Hanifin1, S J Tofte.   

Abstract

Atopic dermatitis (AD) is complicated and often difficult to manage. Effective therapy is commonly impeded by 3 ambivalencies: (1) prioritization of skin care versus allergy treatment; (2) uncertainty about optimal bathing and moisturizing, and (3) hesitation about the use of adequate topical corticosteroid therapies. With a confident, well-planned approach, effective therapy management may be achieved. On initial assessment, an evaluation form is a tool to keep the focus on important history and physical features critical for the diagnosis and to review trigger factors and past therapies. Patients and parents must be educated to become more aware of the trigger factors that may lead to an exacerbation of their disease. Errors in bathing and moisturizing are the major cause of persistent AD, and the confusing paradox that water is both good and bad for the skin must be resolved to achieve therapeutic success. Avoidance/approach conflicts regarding recommendations of topical steroid use has a detrimental effect on patient outcomes. With the proper use of mid-strength topical agents and with the recent development of topical macrolides for use in AD, effective management for this disease can be realized.

Entities:  

Mesh:

Year:  1999        PMID: 10482863     DOI: 10.1016/s0091-6749(99)70054-0

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  6 in total

1.  Eczema.

Authors:  B R Krafchik
Journal:  Paediatr Child Health       Date:  2000-03       Impact factor: 2.253

Review 2.  Allergen Immunotherapy and Atopic Dermatitis: the Good, the Bad, and the Unknown.

Authors:  Patrick Rizk; Mario Rodenas; Anna De Benedetto
Journal:  Curr Allergy Asthma Rep       Date:  2019-11-27       Impact factor: 4.806

3.  Prehydration is effective for rapid control of recalcitrant atopic dermatitis.

Authors:  Tamar Hajar; Jon M Hanifin; Susan J Tofte; Eric L Simpson
Journal:  Dermatitis       Date:  2014 Mar-Apr       Impact factor: 4.845

4.  Twice weekly fluticasone propionate added to emollient maintenance treatment to reduce risk of relapse in atopic dermatitis: randomised, double blind, parallel group study.

Authors:  John Berth-Jones; Robert J Damstra; Stefan Golsch; John K Livden; Oliver Van Hooteghem; Fulvio Allegra; Christine A Parker
Journal:  BMJ       Date:  2003-06-21

5.  Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice.

Authors:  K Kasutani; E Fujii; S Ohyama; H Adachi; M Hasegawa; H Kitamura; N Yamashita
Journal:  Br J Pharmacol       Date:  2014-09-05       Impact factor: 8.739

6.  Anti-Atopic Effect of Acorn Shell Extract on Atopic Dermatitis-Like Lesions in Mice and Its Active Phytochemicals.

Authors:  Sullim Lee; Hyun Jegal; Sim-Kyu Bong; Kyeong-No Yoon; No-June Park; Myoung-Sook Shin; Min Hye Yang; Yong Kee Kim; Su-Nam Kim
Journal:  Biomolecules       Date:  2019-12-29
  6 in total

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