Literature DB >> 1047990

[ANT(4')I: a new aminoglycoside nucleotidyltransferase found in "staphylococcus aureus" (author's transl)].

F Le Goffic, B Baca, C J Soussy, A Dublanchet, J Duval.   

Abstract

A new nucleotidyltransferase has been obtained from clinical isolates of kanamycin, amikacin, tobramycin, neomycin and lividomycin resistant strains of Staphylococcus aureus. The enzyme has been purified by affinity chromatography then characterized in a kinetic and physicochemical point of view. The results obtained support that the target of this enzyme is the 4'-hydroxyl group of a number of aminoglycosides. We propose to call it ANT(4')I.

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Year:  1976        PMID: 1047990

Source DB:  PubMed          Journal:  Ann Microbiol (Paris)        ISSN: 0300-5410


  4 in total

1.  2"-O-phosphorylation of gentamicin components by a Staphylococcus aureus strain carrying a plasmid.

Authors:  A Martel; N Moreau; M L Capmau; C J Soussy; J Duval
Journal:  Antimicrob Agents Chemother       Date:  1977-07       Impact factor: 5.191

Review 2.  Aminoglycosides: An Overview.

Authors:  Kevin M Krause; Alisa W Serio; Timothy R Kane; Lynn E Connolly
Journal:  Cold Spring Harb Perspect Med       Date:  2016-06-01       Impact factor: 6.915

3.  Emergence of 4',4"-aminoglycoside nucleotidyltransferase in enterococci.

Authors:  C Carlier; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1990-08       Impact factor: 5.191

4.  Gene homogeneity for aminoglycoside-modifying enzymes in gram-positive cocci.

Authors:  H Ounissi; E Derlot; C Carlier; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191

  4 in total

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