Literature DB >> 10476857

Rational herbicide design by inhibition of tryptophan biosynthesis.

J Finn1, C Langevine, I Birk, J Birk, K Nickerson, S Rodaway.   

Abstract

Compounds designed to mimic the tryptophan synthase alpha subunit reactive intermediate were found to be potent inhibitors of the enzyme. These compounds are herbicidal and the herbicidal mode of action was demonstrated to be due to disruption of tryptophan biosynthesis.

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Year:  1999        PMID: 10476857     DOI: 10.1016/s0960-894x(99)00340-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  Tryptophan synthase: a mine for enzymologists.

Authors:  Samanta Raboni; Stefano Bettati; Andrea Mozzarelli
Journal:  Cell Mol Life Sci       Date:  2009-04-22       Impact factor: 9.261

2.  Protocol: analytical methods for visualizing the indolic precursor network leading to auxin biosynthesis.

Authors:  Molly Tillmann; Qian Tang; Jerry D Cohen
Journal:  Plant Methods       Date:  2021-06-22       Impact factor: 4.993

  2 in total

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