| Literature DB >> 10475192 |
B Vaidya, H Imrie, P Perros, J Dickinson, M I McCarthy, P Kendall-Taylor, S H Pearce.
Abstract
Smoking and demographic variables are known to be risk factors for the development of thyroid-associated orbitopathy (TAO) among patients with Graves' hyperthyroidism, but a firm genetic basis for TAO has not been established. We show that the presence and severity of TAO are associated with an allele of the cytotoxic T lymphocyte antigen-4-gene.Entities:
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Year: 1999 PMID： 10475192 DOI： 10.1016/S0140-6736(99)01465-8
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321