Literature DB >> 10474215

Making drugs out of oligonucleotides: a brief review and perspective.

P D Cook1.   

Abstract

I provide a brief review and perspective thoughts concerning the antisense oligonucleotide, drug discovery paradigm.

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Year:  1999        PMID： 10474215     DOI： 10.1080/07328319908044652

Source DB:  PubMed          Journal:  Nucleosides Nucleotides        ISSN： 0732-8311


  6 in total

Review 1.  Chemical approaches to control gene expression.

Authors:  J M Gottesfeld; J M Turner; P B Dervan
Journal:  Gene Expr       Date:  2000

2.  2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivo.

Authors:  Thazha P Prakash; Joseph F Johnston; Mark J Graham; Thomas P Condon; Muthiah Manoharan
Journal:  Nucleic Acids Res       Date:  2004-02-03       Impact factor: 16.971

3.  Mapping of accessible sites for oligonucleotide hybridization on hepatitis delta virus ribozymes.

Authors:  J Wrzesinski; M Legiewicz; J Ciesiołka
Journal:  Nucleic Acids Res       Date:  2000-04-15       Impact factor: 16.971

4.  Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA.

Authors:  Miriam Frieden; Signe M Christensen; Nikolaj D Mikkelsen; Christoph Rosenbohm; Charlotte A Thrue; Majken Westergaard; Henrik F Hansen; Henrik Ørum; Troels Koch
Journal:  Nucleic Acids Res       Date:  2003-11-01       Impact factor: 16.971

5.  Quantum mechanical studies of DNA and LNA.

Authors:  Troels Koch; Irene Shim; Morten Lindow; Henrik Ørum; Henrik G Bohr
Journal:  Nucleic Acid Ther       Date:  2014-02-03       Impact factor: 5.486

6.  Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif.

Authors:  Miaomiao Fan; Yijun Zhang; Zhuoqiong Huang; Jun Liu; Xuemin Guo; Hui Zhang; Haihua Luo
Journal:  PLoS One       Date:  2014-09-24       Impact factor: 3.240
  6 in total

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