Literature DB >> 10472625

Does formate reduce alpha-ketoglutarate and ammonia to glutamate?

Q Maughan1, S L Miller.   

Abstract

The reported reduction of alpha-ketoglutarate and ammonia by formate is much slower than described (Morowitz et al., 1995). The formate reduction if any is small under these conditions. Glutamate is produced from a reduction by a second molecule of alpha-ketoglutarate involving an oxidative decarboxylation.

Entities:  

Keywords:  NASA Discipline Exobiology; Non-NASA Center

Mesh：

Substances：

Year:  1999        PMID： 10472625     DOI： 10.1023/a:1006534305943

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN： 0169-6149            Impact factor:   1.950


  17 in total

1.  Prebiotic transamination.

Authors:  J C Bishop; S D Cross; T G Waddell
Journal:  Orig Life Evol Biosph       Date:  1997-08       Impact factor: 1.950

2.  The synthesis of glutamic acid in the absence of enzymes: implications for biogenesis.

Authors:  H Morowitz; E Peterson; S Chang
Journal:  Orig Life Evol Biosph       Date:  1995-08       Impact factor: 1.950

3.  On the Evolution of Biochemical Syntheses.

Authors:  N H Horowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1945-06       Impact factor: 11.205

4.  A possible prebiotic synthesis of thymine: uracil-formaldehyde-formic acid reaction.

Authors:  A S Choughuley; A S Subbaraman; Z A Kazi; M S Chadha
Journal:  Biosystems       Date:  1977-09       Impact factor: 1.973

Review 5.  Enzyme recruitment in evolution of new function.

Authors:  R A Jensen
Journal:  Annu Rev Microbiol       Date:  1976       Impact factor: 15.500

6.  Prebiotic synthesis of orotic acid parallel to the biosynthetic pathway.

Authors:  Y Yamagata; K Sasaki; O Takaoka; S Sano; K Inomata; K Kanemitsu; Y Inoue; I Matsumoto
Journal:  Orig Life Evol Biosph       Date:  1990       Impact factor: 1.950

7.  Evolution of the biosynthesis of the branched-chain amino acids.

Authors:  A D Keefe; A Lazcano; S L Miller
Journal:  Orig Life Evol Biosph       Date:  1995-06       Impact factor: 1.950

8.  Prebiotic synthesis of diaminopyrimidine and thiocytosine.

Authors:  M P Robertson; M Levy; S L Miller
Journal:  J Mol Evol       Date:  1996-12       Impact factor: 2.395

9.  An efficient prebiotic synthesis of cytosine and uracil.

Authors:  M P Robertson; S L Miller
Journal:  Nature       Date:  1995-06-29       Impact factor: 49.962

10.  Prebiotic synthesis of 5-substituted uracils: a bridge between the RNA world and the DNA-protein world.

Authors:  M P Robertson; S L Miller
Journal:  Science       Date:  1995-05-05       Impact factor: 47.728
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.