Literature DB >> 10471767

Gene therapy for osteoinduction.

A A Scaduto1, J R Lieberman.   

Abstract

One application of gene therapy that holds great promise is the stimulation of bone formation. Gene therapy offers several potential advantages over other methods of osteoinduction and current research suggests that it may be a feasible treatment option for the orthopedic surgeon in the near future. This article reviews the basic concepts and strategies of gene therapy and evaluates the current research using gene therapy to induce bone formation and enhance healing.

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Year:  1999        PMID： 10471767     DOI： 10.1016/s0030-5898(05)70115-2

Source DB:  PubMed          Journal:  Orthop Clin North Am        ISSN： 0030-5898            Impact factor:   2.472


  8 in total

Review 1.  Stem cells for repair of cartilage and bone: the next challenge in osteoarthritis and rheumatoid arthritis.

Authors:  C Jorgensen; D Noel; F Apparailly; J Sany
Journal:  Ann Rheum Dis       Date:  2001-04       Impact factor: 19.103

Review 2.  The potential of gene therapy for fracture healing in osteoporosis.

Authors:  M Egermann; E Schneider; C H Evans; A W Baltzer
Journal:  Osteoporos Int       Date:  2005-01-15       Impact factor: 4.507

3.  Tracking expression of virally mediated BMP-2 in gene therapy for bone repair.

Authors:  Seth C Gamradt; Nobuhiro Abe; Matthew E Bahamonde; Yu-Po Lee; Scott D Nelson; Karen M Lyons; Jay R Lieberman
Journal:  Clin Orthop Relat Res       Date:  2006-09       Impact factor: 4.176

4.  Gene gun transferring-bone morphogenetic protein 2 (BMP-2) gene enhanced bone fracture healing in rabbits.

Authors:  Wenju Li; Haifeng Wei; Chunmei Xia; Xiaomeng Zhu; Guozhu Hou; Feng Xu; Xinghua Song; Yulin Zhan
Journal:  Int J Clin Exp Med       Date:  2015-11-15

Review 5.  Gene therapy for bone healing: lessons learned and new approaches.

Authors:  Rodolfo E De la Vega; Aysegul Atasoy-Zeybek; Joseph A Panos; Martijn VAN Griensven; Christopher H Evans; Elizabeth R Balmayor
Journal:  Transl Res       Date:  2021-05-05       Impact factor: 10.171

6.  Bone Morphogenetic Protein-9 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via the JNK Pathway.

Authors:  Pei Wang; Yanen Wang; Weizhong Tang; Xingxing Wang; Yanan Pang; Su Yang; Yibo Wei; Haochen Gao; Dalin Wang; Zhizhong Cao
Journal:  PLoS One       Date:  2017-01-04       Impact factor: 3.240

7.  Construction and characterization of a recombinant human adenovirus vector expressing bone morphogenetic protein 2.

Authors:  Zheng Zhang; Guoxian Wang; Chen Li; Danping Liu
Journal:  Exp Ther Med       Date:  2013-06-17       Impact factor: 2.447

8.  Repair of large segmental bone defects: BMP-2 gene activated muscle grafts vs. autologous bone grafting.

Authors:  Oliver B Betz; Volker M Betz; Christian Schröder; Rainer Penzkofer; Michael Göttlinger; Susanne Mayer-Wagner; Peter Augat; Volkmar Jansson; Peter E Müller
Journal:  BMC Biotechnol       Date:  2013-08-08       Impact factor: 2.563
  8 in total

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