S M Pezzotto1, L Poletto. 1. Institute of Immunology, School of Medicine, National University of Rosario, Argentina. smpezzotto@mailcity.com
Abstract
BACKGROUND: Male age-adjusted lung cancer mortality rate is high in Rosario City, Argentina (62.7 per 100,000). METHODS: Case-control study involving interviews with 367 male lung cancer patients and 576 controls. RESULTS: The histological distribution detected was: squamous cell 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no specified cell type 14%. When comparing with the group unlikely to be exposed to occupational carcinogens, a 60% increase in risk was observed for the remaining occupations (P < 0.008). Risks were high for drivers (OR=1.9, CI: 1.1-4.0), construction (OR=2.5, CI: 1.0-5.9), and agricultural workers also (OR=1.8, CI: 1. 1-3.1). In regard to squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR=2.9, CI: 1.0-10.1) and mechanics (OR=1.8, CI: 0.9-4.2). Smoking was not a substantial confounding effect. CONCLUSIONS: Occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City. Copyright 1999 Wiley-Liss, Inc.
BACKGROUND: Male age-adjusted lung cancer mortality rate is high in Rosario City, Argentina (62.7 per 100,000). METHODS: Case-control study involving interviews with 367 male lung cancerpatients and 576 controls. RESULTS: The histological distribution detected was: squamous cell 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no specified cell type 14%. When comparing with the group unlikely to be exposed to occupational carcinogens, a 60% increase in risk was observed for the remaining occupations (P < 0.008). Risks were high for drivers (OR=1.9, CI: 1.1-4.0), construction (OR=2.5, CI: 1.0-5.9), and agricultural workers also (OR=1.8, CI: 1. 1-3.1). In regard to squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR=2.9, CI: 1.0-10.1) and mechanics (OR=1.8, CI: 0.9-4.2). Smoking was not a substantial confounding effect. CONCLUSIONS: Occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City. Copyright 1999 Wiley-Liss, Inc.
Authors: Virissa Lenters; Ioannis Basinas; Laura Beane-Freeman; Paolo Boffetta; Harvey Checkoway; David Coggon; Lützen Portengen; Malcolm Sim; Inge M Wouters; Dick Heederik; Roel Vermeulen Journal: Cancer Causes Control Date: 2009-12-12 Impact factor: 2.506
Authors: Neela Guha; Franco Merletti; Nelson Kyle Steenland; Andrea Altieri; Vincent Cogliano; Kurt Straif Journal: Environ Health Perspect Date: 2009-10-22 Impact factor: 9.031
Authors: G Menvielle; D Luce; J Févotte; I Bugel; C Salomon; P Goldberg; M-A Billon-Galland; M Goldberg Journal: Occup Environ Med Date: 2003-08 Impact factor: 4.402
Authors: Aude Lacourt; Javier Pintos; Jérôme Lavoué; Lesley Richardson; Jack Siemiatycki Journal: BMC Public Health Date: 2015-09-22 Impact factor: 3.295
Authors: Dario Consonni; Sara De Matteis; Jay H Lubin; Sholom Wacholder; Margaret Tucker; Angela Cecilia Pesatori; Neil E Caporaso; Pier Alberto Bertazzi; Maria Teresa Landi Journal: Am J Epidemiol Date: 2010-01-04 Impact factor: 4.897
Authors: Eric Vallières; Javier Pintos; Jérôme Lavoué; Marie-Élise Parent; Bernard Rachet; Jack Siemiatycki Journal: Cancer Med Date: 2012-06-07 Impact factor: 4.452