| Literature DB >> 10467124 |
M F Carlier1, A Ducruix, D Pantaloni.
Abstract
The molecular link between the signalling pathway regulating the formation of filopodia and the initiation of local actin polymerization has been elucidated: N-WASP, a close homologue of WASP, which is the product of the gene responsible for the Wiskott-Aldrich syndrome, mediates a direct connection between the small G-protein Cdc42 and the Arp2/3 complex.Entities:
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Year: 1999 PMID： 10467124 DOI： 10.1016/s1074-5521(99)80107-0
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521