Literature DB >> 10459355

11q13 is a cytogenetically promiscuous site in hematologic malignancies.

K F Wong1.   

Abstract

11q13 translocation has been described in mantle cell lymphoma in the form of t(11;14) (q13;q32), with rearrangement and over-expression of the cyclin D1 gene. Recently, an association between 11q13 and acute myeloid leukemia is recognized. We describe the occurrence of 11q13 translocations in both acute leukemias and myelodysplastic syndrome, and suggest that other genetic mechanisms unrelated to cyclin D1 may be involved in the tumorigensis. Furthermore, 11q13 appears to be a cytogenetically promiscuous site involved in reciprocal translocations with different chromosomes in both myeloid and lymphoid malignancies.

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Mesh：

Year:  1999        PMID： 10459355     DOI： 10.1016/s0165-4608(98)00285-4

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  7 in total

1.  Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein.

Authors:  E Kolpakova; E Frengen; T Stokke; S Olsnes
Journal:  Biochem J       Date:  2000-12-15       Impact factor: 3.857

2.  Translocation t(6;14) as the sole chromosomal abnormality in adenoid cystic carcinoma of the base of tongue.

Authors:  Diana Bell; Yi-Jue Zhao; Pulivarthi H Rao; Randal S Weber; Adel K El-Naggar
Journal:  Head Neck Pathol       Date:  2007-10-26

3.  Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance.

Authors:  Yoshitsugu Mitani; Jie Li; Pulivarthi H Rao; Yi-Jue Zhao; Diana Bell; Scott M Lippman; Randal S Weber; Carlos Caulin; Adel K El-Naggar
Journal:  Clin Cancer Res       Date:  2010-08-11       Impact factor: 12.531

4.  Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster.

Authors:  J A Yoder; M G Mueller; S Wei; B C Corliss; D M Prather; T Willis; R T Litman; J Y Djeu; G W Litman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-29       Impact factor: 11.205

Review 5.  Cytogenetic instability in childhood acute lymphoblastic leukemia survivors.

Authors:  María Sol Brassesco; Danilo Jordão Xavier; Marjori Leiva Camparoto; Ana Paula Montaldi; Paulo Roberto D'Auria Vieira de Godoy; Carlos Alberto Scrideli; Luiz Gonzaga Tone; Elza Tiemi Sakamoto-Hojo
Journal:  J Biomed Biotechnol       Date:  2010-08-31

6.  Increased Expression of Phosphorylated FADD in Anaplastic Large Cell and Other T-Cell Lymphomas.

Authors:  Suketu Patel; Derek Murphy; Eugenia Haralambieva; Zainalabideen A Abdulla; Kah Keng Wong; Hong Chen; Edith Gould; Giovanna Roncador; Chris Hatton; Amanda P Anderson; Alison H Banham; Karen Pulford
Journal:  Biomark Insights       Date:  2014-09-03

7.  A Rare t(5;11)(q35;q13) Translocation in an Elderly Patient With Acute Myeloid Leukemia With Maturation: A Case Report.

Authors:  Masahiro Manabe; Yuuji Hagiwara; Reiko Asada; Dai Momose; Yasuyoshi Sugano; Ki-Ryang Koh
Journal:  J Hematol (Brossard)       Date:  2018-05-10
  7 in total

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