Literature DB >> 10458279

Injectable bone substitute using a hydrophilic polymer.

P Weiss1, O Gauthier, J M Bouler, G Grimandi, G Daculsi.   

Abstract

We studied a new injectable biomaterial for bone and dental surgery consisting of a hydrophilic polymer as matrix and bioactive calcium phosphate (CaP) ceramics as fillers. This material is composed of complex fluids whose flow is determined by the laws of rheology. We investigated the macromolecular effects on this composite in a tube. The stability of the polymer and the mixture is essential to the production of a ready-to-use injectable biomaterial. These flow properties are necessary to obtain CaP bioactivity in a dental canal or bone defect during percutaneous surgery. Macromolecules provide spaces between CaP ceramic granules and facilitate the role of the biological agents of bone substitution.

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Year:  1999        PMID： 10458279     DOI： 10.1016/s8756-3282(99)00146-5

Source DB:  PubMed          Journal:  Bone        ISSN： 1873-2763            Impact factor:   4.398


  13 in total

1.  In vitro and in vivo bactericidal activities of vancomycin dispersed in porous biodegradable poly(epsilon-caprolactone) microparticles.

Authors:  Anne-Marie Le Ray; Hélène Gautier; Marie-Katel Laty; Guy Daculsi; Christian Merle; Cédric Jacqueline; Antoine Hamel; Jocelyne Caillon
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

2.  Kinetic studies of a composite carbon nanotube-hydrogel for tissue engineering by rheological methods.

Authors:  Fan Xie; Pierre Weiss; Olivier Chauvet; Jean Le Bideau; Jean François Tassin
Journal:  J Mater Sci Mater Med       Date:  2010-01-06       Impact factor: 3.896

Review 3.  Biocomposites and hybrid biomaterials based on calcium orthophosphates.

Authors:  Sergey V Dorozhkin
Journal:  Biomatter       Date:  2011 Jul-Sep

4.  Interaction between hydroxypropyl methylcellulose and biphasic calcium phosphate after steam sterilisation: capillary gas chromatography studies.

Authors:  X Bourges; M Schmitt; Y Amouriq; G Daculsi; G Legeay; P Weiss
Journal:  J Biomater Sci Polym Ed       Date:  2001       Impact factor: 3.517

5.  Injection of calcium phosphate pastes: prediction of injection force and comparison with experiments.

Authors:  Ahmed Fatimi; Jean-François Tassin; Julia Bosco; Rémi Deterre; Monique A V Axelos; Pierre Weiss
Journal:  J Mater Sci Mater Med       Date:  2012-04-24       Impact factor: 3.896

6.  Characterization of polymeric solutions as injectable vehicles for hydroxyapatite microspheres.

Authors:  Serafim M Oliveira; Isabel F Almeida; Paulo C Costa; Cristina C Barrias; M Rosa Pena Ferreira; M Fernanda Bahia; Mário A Barbosa
Journal:  AAPS PharmSciTech       Date:  2010-05-19       Impact factor: 3.246

7.  The role of adipose-derived stromal cells and hydroxypropylmethylcellulose in engineering cartilage tissue in vivo.

Authors:  YuQiao Xu; Jing Zhang; Yu Ma; Yu Han; Jie Min; YuanYuan Liang; DaQing Zhao; JianHua Qiu
Journal:  Cytotechnology       Date:  2013-11-28       Impact factor: 2.058

8.  Developments in injectable multiphasic biomaterials. The performance of microporous biphasic calcium phosphate granules and hydrogels.

Authors:  G Daculsi; A P Uzel; P Weiss; E Goyenvalle; E Aguado
Journal:  J Mater Sci Mater Med       Date:  2009-11-01       Impact factor: 3.896

9.  Skin sensitization study of two hydroxypropyl methylcellulose components (Benecel and E4M) of an injectable bone substitute in guinea pigs.

Authors:  Y Amouriq; X Bourges; P Weiss; J Bosco; J-M Bouler; G Daculsi
Journal:  J Mater Sci Mater Med       Date:  2002-02       Impact factor: 3.896

Review 10.  Calcium Orthophosphate-Containing Biocomposites and Hybrid Biomaterials for Biomedical Applications.

Authors:  Sergey V Dorozhkin
Journal:  J Funct Biomater       Date:  2015-08-07
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