Literature DB >> 10456375

Comparison of in vivo 1H MRS of human brain tumours with 1H HR-MAS spectroscopy of intact biopsy samples in vitro.

S J Barton1, F A Howe, A M Tomlins, S A Cudlip, J K Nicholson, B A Bell, J R Griffiths.   

Abstract

High resolution magic angle spinning (MAS) 1H nuclear magnetic resonance (NMR) spectroscopy has been employed to study intact human brain tumour tissue and comparison with the corresponding in vivo spectrum has been made. Two dimensional 1H MAS-NMR measurements, including J-resolved and homonuclear shift correlation spectra, were obtained to aid metabolite signal assignment. MAS gave greatly improved line-shape and reduced line-width in comparison to conventional high resolution in vivo 1H MRS of intact tissue, permitting the simultaneous detection of cellular lipids and metabolites. The technique provides the most direct method for comparison of in vivo spectra with high resolution spectra in vitro and hence allows more reliable peak assignment of in vivo 1H MRS spectra.

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Year:  1999        PMID： 10456375     DOI： 10.1007/bf02590529

Source DB:  PubMed          Journal:  MAGMA        ISSN： 0968-5243            Impact factor:   2.310


  17 in total

1.  Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy.

Authors:  Y Kinoshita; A Yokota
Journal:  NMR Biomed       Date:  1997-01       Impact factor: 4.044

2.  3D localized 2D NMR spectroscopy on an MRI scanner.

Authors:  L N Ryner; J A Sorenson; M A Thomas
Journal:  J Magn Reson B       Date:  1995-05

3.  The effect of sample freezing on proton magic-angle spinning NMR spectra of biological tissue.

Authors:  D A Middleton; D P Bradley; S C Connor; P G Mullins; D G Reid
Journal:  Magn Reson Med       Date:  1998-07       Impact factor: 4.668

4.  Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge.

Authors:  J W van der Veen; R de Beer; P R Luyten; D van Ormondt
Journal:  Magn Reson Med       Date:  1988-01       Impact factor: 4.668

5.  Quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy.

Authors:  L L Cheng; M J Ma; L Becerra; T Ptak; I Tracey; A Lackner; R G González
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

Review 6.  Towards a method for automated classification of 1H MRS spectra from brain tumours.

Authors:  A R Tate; J R Griffiths; I Martínez-Pérez; A Moreno; I Barba; M E Cabañas; D Watson; J Alonso; F Bartumeus; F Isamat; I Ferrer; F Vila; E Ferrer; A Capdevila; C Arús
Journal:  NMR Biomed       Date:  1998 Jun-Aug       Impact factor: 4.044

7.  Pattern recognition analysis of 1H NMR spectra from perchloric acid extracts of human brain tumor biopsies.

Authors:  R J Maxwell; I Martínez-Pérez; S Cerdán; M E Cabañas; C Arús; A Moreno; A Capdevila; E Ferrer; F Bartomeus; A Aparicio; G Conesa; J M Roda; F Carceller; J M Pascual; S L Howells; R Mazucco; J R Griffiths
Journal:  Magn Reson Med       Date:  1998-06       Impact factor: 4.668

8.  750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma.

Authors:  J K Nicholson; P J Foxall; M Spraul; R D Farrant; J C Lindon
Journal:  Anal Chem       Date:  1995-03-01       Impact factor: 6.986

9.  In vivo, ex vivo, and in vitro one- and two-dimensional nuclear magnetic resonance spectroscopy of an intracerebral glioma in rat brain: assignment of resonances.

Authors:  C Rémy; C Arús; A Ziegler; E S Lai; A Moreno; Y Le Fur; M Décorps
Journal:  J Neurochem       Date:  1994-01       Impact factor: 5.372

10.  Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.

Authors:  C L Florian; N E Preece; K K Bhakoo; S R Williams; M Noble
Journal:  NMR Biomed       Date:  1995-09       Impact factor: 4.044
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  17 in total

Review 1.  Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer.

Authors:  J Kurhanewicz; D B Vigneron; S J Nelson
Journal:  Neoplasia       Date:  2000 Jan-Apr       Impact factor: 5.715

2.  High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues.

Authors:  Olaf Beckonert; Muireann Coen; Hector C Keun; Yulan Wang; Timothy M D Ebbels; Elaine Holmes; John C Lindon; Jeremy K Nicholson
Journal:  Nat Protoc       Date:  2010-05-13       Impact factor: 13.491

3.  Minimization of spectral pattern changes during HRMAS experiments at 37 degrees celsius by prior focused microwave irradiation.

Authors:  Myriam Davila; Ana Paula Candiota; Martí Pumarola; Carles Arus
Journal:  MAGMA       Date:  2012-10       Impact factor: 2.310

Review 4.  The application of NMR-based metabonomics in neurological disorders.

Authors:  Elaine Holmes; Tsz M Tsang; Sarah J Tabrizi
Journal:  NeuroRx       Date:  2006-07

Review 5.  Metabonomics techniques and applications to pharmaceutical research & development.

Authors:  John C Lindon; Elaine Holmes; Jeremy K Nicholson
Journal:  Pharm Res       Date:  2006-05-25       Impact factor: 4.200

6.  Elevated glutamate, glutamine and GABA levels and reduced taurine level in a schizophrenia model using an in vitro proton nuclear magnetic resonance method.

Authors:  Jingyu Yang; Huiling Guo; Dandan Sun; Jia Duan; Xiaoping Rao; Fuqiang Xu; Anne Manyande; Yanqing Tang; Jie Wang; Fei Wang
Journal:  Am J Transl Res       Date:  2019-09-15       Impact factor: 4.060

7.  Preoperative proton MR spectroscopic imaging of brain tumors: correlation with histopathologic analysis of resection specimens.

Authors:  C Dowling; A W Bollen; S M Noworolski; M W McDermott; N M Barbaro; M R Day; R G Henry; S M Chang; W P Dillon; S J Nelson; D B Vigneron
Journal:  AJNR Am J Neuroradiol       Date:  2001-04       Impact factor: 3.825

8.  Concentration profiling in rat tissue by high-resolution magic-angle spinning NMR spectroscopy: investigation of a model drug.

Authors:  Laura H Lucas; Sarah F Wilson; Craig E Lunte; Cynthia K Larive
Journal:  Anal Chem       Date:  2005-05-01       Impact factor: 6.986

9.  Brain tumor evaluation and segmentation by in vivo proton spectroscopy and relaxometry.

Authors:  Miguel Martín-Landrove; Finita Mayobre; Igor Bautista; Raúl Villalta
Journal:  MAGMA       Date:  2005-12-30       Impact factor: 2.310

Review 10.  Metabolomics-based methods for early disease diagnostics.

Authors:  G A Nagana Gowda; Shucha Zhang; Haiwei Gu; Vincent Asiago; Narasimhamurthy Shanaiah; Daniel Raftery
Journal:  Expert Rev Mol Diagn       Date:  2008-09       Impact factor: 5.225
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