Literature DB >> 10448150

Host genetic influences on HIV-1 pathogenesis.

N L Michael1.   

Abstract

Cellular entry of HIV-1 is mediated by interaction with CD4 and chemokine receptors that serve as entry coreceptors. The immune response against HIV-1 is regulated by genes of the HLA locus. Genetic polymorphisms in these genes have recently been associated with effects on HIV-1 pathogenesis. The history and implications of these discoveries are described in this review.

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Year:  1999        PMID： 10448150     DOI： 10.1016/S0952-7915(99)80078-8

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  16 in total

1.  Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

Authors:  Mohan Somasundaran; Mark Sharkey; Beda Brichacek; Katherine Luzuriaga; Michael Emerman; John L Sullivan; Mario Stevenson
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-01       Impact factor: 11.205

2.  A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect.

Authors:  Hendrik Huthoff; Atze T Das; Monique Vink; Bep Klaver; Fokla Zorgdrager; Marion Cornelissen; Ben Berkhout
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

Review 3.  Host genetic factors in susceptibility to HIV-1 infection and progression to AIDS.

Authors:  Koushik Chatterjee
Journal:  J Genet       Date:  2010-04       Impact factor: 1.166

Review 4.  Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications.

Authors:  L Buonaguro; M L Tornesello; F M Buonaguro
Journal:  J Virol       Date:  2007-07-18       Impact factor: 5.103

5.  Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression.

Authors:  Jianming Tang; Brent Shelton; Nina J Makhatadze; Yuting Zhang; Margaret Schaen; Leslie G Louie; James J Goedert; Eric C Seaberg; Joseph B Margolick; John Mellors; Richard A Kaslow
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

6.  A statistical model for genetic mapping of viral infection by integrating epidemiological behavior.

Authors:  Yao Li; Arthur Berg; Myron N Chang; Ping Du; Kwangmi Ahn; David Mauger; Duanping Liao; Rongling Wu
Journal:  Stat Appl Genet Mol Biol       Date:  2009-09-09

Review 7.  Genetic variation and HIV-associated neurologic disease.

Authors:  Satinder Dahiya; Bryan P Irish; Michael R Nonnemacher; Brian Wigdahl
Journal:  Adv Virus Res       Date:  2013       Impact factor: 9.937

8.  Conflicting selection pressures on T-cell epitopes in HIV-1 subtype B.

Authors:  Stephanie Jiménez Irausquin; Austin L Hughes
Journal:  Infect Genet Evol       Date:  2011-01-11       Impact factor: 3.342

9.  CCR5 promoter polymorphisms in a Kenyan perinatal human immunodeficiency virus type 1 cohort: association with increased 2-year maternal mortality.

Authors:  G C John; T Bird; J Overbaugh; R Nduati; D Mbori-Ngacha; T Rostron; T Dong; L Kostrikis; B Richardson; S L Rowland-Jones
Journal:  J Infect Dis       Date:  2001-05-31       Impact factor: 5.226

10.  Evidences for viral strain selection in late stages of HIV infection: an analysis of Vpu alleles.

Authors:  Marcos Vinícius Pereira Gondim; Joaquim Xavier da Silva; Francisco Prosdocimi; Eduardo Leonardecz-Neto; Octávio Luiz Franco; Enrique Roberto Argañaraz
Journal:  Protein J       Date:  2012-02       Impact factor: 2.371
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