Literature DB >> 10433387

A review of the effects of microgravity and of hypergravity on aging and longevity.

E Le Bourg1.   

Abstract

This article reviews the literature dealing with the effects of acute or chronic exposure to microgravity (spacecrafts) or hypergravity (centrifuge) on longevity and the aging process. Even if space flights are now common, the effects of these two kinds of environment on aging are still poorly documented, particularly in mammals. However, there is a growing interest for the use of the fruit fly Drosophila melanogaster, and this species may be now considered as a model organism in gravitational biology studies dealing with aging.

Mesh：

Year:  1999        PMID： 10433387     DOI： 10.1016/s0531-5565(99)00004-2

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN： 0531-5565            Impact factor:   4.032


  10 in total

1.  Hormetic protection of Drosophila melanogaster middle-aged male flies from heat stress by mildly stressing them at young age.

Authors:  Eric Le Bourg
Journal:  Naturwissenschaften       Date:  2005-04-16

2.  Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans.

Authors:  Nahui Kim; Catherine M Dempsey; Chih-Jen Kuan; Jim V Zoval; Eyleen O'Rourke; Gary Ruvkun; Marc J Madou; Ji Y Sze
Journal:  Genetics       Date:  2007-08-24       Impact factor: 4.562

Review 3.  Remote Controlled Autonomous Microgravity Lab Platforms for Drug Research in Space.

Authors:  Shimon Amselem
Journal:  Pharm Res       Date:  2019-11-18       Impact factor: 4.200

4.  Unconscious mind activates central cardiovascular network and promotes adaptation to microgravity possibly anti-aging during 1-year-long spaceflight.

Authors:  Kuniaki Otsuka; Germaine Cornelissen; Satoshi Furukawa; Koichi Shibata; Yutaka Kubo; Koh Mizuno; Tatsuya Aiba; Hiroshi Ohshima; Chiaki Mukai
Journal:  Sci Rep       Date:  2022-07-13       Impact factor: 4.996

5.  The hormetic effects of hypergravity on longevity and aging.

Authors:  Nadège Minois
Journal:  Dose Response       Date:  2006-08-19       Impact factor: 2.658

6.  Suboptimal evolutionary novel environments promote singular altered gravity responses of transcriptome during Drosophila metamorphosis.

Authors:  Raul Herranz; Oliver J Larkin; Richard J A Hill; Irene Lopez-Vidriero; Jack J W A van Loon; F Javier Medina
Journal:  BMC Evol Biol       Date:  2013-06-27       Impact factor: 3.260

7.  Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster.

Authors:  Lingling Ma; Jun Ma; Kanyan Xu
Journal:  PLoS One       Date:  2015-03-23       Impact factor: 3.240

Review 8.  Human Pathophysiological Adaptations to the Space Environment.

Authors:  Gian C Demontis; Marco M Germani; Enrico G Caiani; Ivana Barravecchia; Claudio Passino; Debora Angeloni
Journal:  Front Physiol       Date:  2017-08-02       Impact factor: 4.566

9.  Gravitational stress during parabolic flights reduces the number of circulating innate and adaptive leukocyte subsets in human blood.

Authors:  Ulrik Stervbo; Toralf Roch; Tina Kornprobst; Birgit Sawitzki; Gerald Grütz; Andreas Wilhelm; Francis Lacombe; Kaoutar Allou; Markus Kaymer; Antoine Pacheco; Jacques Vigne; Timm H Westhoff; Felix S Seibert; Nina Babel
Journal:  PLoS One       Date:  2018-11-14       Impact factor: 3.240

10.  Repeated Changes to the Gravitational Field Negatively Affect the Serum Concentration of Select Growth Factors and Cytokines.

Authors:  Ulrik Stervbo; Toralf Roch; Timm H Westhoff; Ludmyla Gayova; Andrii Kurchenko; Felix S Seibert; Nina Babel
Journal:  Front Physiol       Date:  2019-04-17       Impact factor: 4.566
  10 in total

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