Literature DB >> 10424995

Aortic valve repair by cusp extension with the use of fresh autologous pericardium in children with rheumatic aortic insufficiency.

A Kalangos1, M Beghetti, A Baldovinos, D Vala, T Bichel, B Mermillod, N Murith, I Oberhansli, B Friedli, B Faidutti.   

Abstract

OBJECTIVES: Our goal was to evaluate the midterm results of aortic valve repair by a more sophisticated tailoring of cusp extension-taking into account the dimensions of the native aortic cusps-with the use of fresh autologous pericardium. PATIENTS AND METHODS: Forty-one children who had severe rheumatic aortic insufficiency (mean age 11.5 +/- 2.7 years) underwent aortic valve repair by means of this cusp extension technique over a 5-year period. Twenty-four of them underwent concomitant mitral valve repair for associated rheumatic mitral valve disease. All children were then followed up by transthoracic echocardiography before discharge, at 3 and 6 months after the operation, and at yearly intervals thereafter.
RESULTS: Follow-up was complete in all patients and ranged from 3 months to 5 years (median 3 years). No operative and no early postoperative deaths occurred. Only 1 patient died, 9 months after the operation, of septicemia and multiple organ failure. Actuarial survival was 97% at 1 year and has remained unchanged at 3 years. On discharge, the degree of aortic insufficiency was grade 0 for 27 children and grade I for 14. Exacerbation of aortic insufficiency from grade I to grade II was observed in only 1 patient, and none of the children required reoperation for aortic insufficiency during the follow-up period. Mean peak systolic aortic valve gradients at discharge were lower than preoperative values (P =.04), and no significant increase in the peak systolic transvalvular gradient was detected thereafter during the follow-up period. Mean left ventricular dimensions were significantly reduced at discharge when compared with preoperative values (P <.0001).
CONCLUSIONS: Functional results of aortic valve repair with cusp extension using fresh pericardium have been satisfactory at medium term, particularly in children with a small aortic anulus at the time of initial repair, because the expansion potential of fresh autologous pericardium is equivalent to that of the growing sinotubular junction and aortic anulus diameters.

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Year:  1999        PMID: 10424995     DOI: 10.1016/S0022-5223(99)70212-6

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  5 in total

Review 1.  Aortic valve repair update.

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Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-02-05

2.  Valvuloplasty for aortic valve regurgitation resulting from cusp prolapse.

Authors:  S Nagamine; S Shinozaki; K Ohsaka; H Kakihata
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2001-03

3.  Guidelines for sizing pericardium for aortic valve leaflet grafts.

Authors:  Peter E Hammer; Pedro J del Nido
Journal:  Ann Thorac Surg       Date:  2013-07       Impact factor: 4.330

4.  Structural Isomerism of the Aortic Valve: Bicuspidization Redux.

Authors:  Thomas G Gleason
Journal:  Ann Thorac Surg       Date:  2019-12-19       Impact factor: 4.330

5.  Aortic valve repair for the treatment of rheumatic aortic valve disease: a systematic review and meta-analysis.

Authors:  Meng Zhao; Yihu Tang; Luo Li; Yawei Dai; Jieyu Lu; Xiang Liu; Jingxin Zhou; Yanhu Wu
Journal:  Sci Rep       Date:  2022-01-13       Impact factor: 4.379

  5 in total

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