Literature DB >> 10424537

Wegener's granulomatosis and alpha1-antitrypsin-deficiency emphysema: proteinase-related diseases.

V T Barnett1, M Sekosan, A Khurshid.   

Abstract

Wegener's granulomatosis (WG) and alpha1-antitrypsin (alpha1-AT)-deficiency emphysema are both uncommon disorders. A relationship may exist between these diseases involving the proteinase and antiproteinase balance in the lung. A case is presented of WG and alpha1-AT-deficiency emphysema occurring in the same patient. Previous studies concerning the correlation between abnormal alpha1-AT alleles and WG are discussed. Potential mechanisms for the relationship and recommendations for screening are given.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10424537     DOI： 10.1378/chest.116.1.253

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  3 in total

1.  α1-Antitrypsin deficiency in a patient diagnosed with granulomatosis with polyangiitis.

Authors:  Hanine Inaty; Senada Arabelovic
Journal:  BMJ Case Rep       Date:  2013-04-25

2.  The prevalence of alpha-1 antitrypsin deficiency in Ireland.

Authors:  Tomás P Carroll; Catherine A O'Connor; Olwen Floyd; Joseph McPartlin; Dermot P Kelleher; Geraldine O'Brien; Borislav D Dimitrov; Valerie B Morris; Clifford C Taggart; Noel G McElvaney
Journal:  Respir Res       Date:  2011-07-13

3.  Identification and characterisation of eight novel SERPINA1 Null mutations.

Authors:  Ilaria Ferrarotti; Tomás P Carroll; Stefania Ottaviani; Anna M Fra; Geraldine O'Brien; Kevin Molloy; Luciano Corda; Daniela Medicina; David R Curran; Noel G McElvaney; Maurizio Luisetti
Journal:  Orphanet J Rare Dis       Date:  2014-11-26       Impact factor: 4.123
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.