Literature DB >> 10422840

Folding of barstar C40A/C82A/P27A and catalysis of the peptidyl-prolyl cis/trans isomerization by human cytosolic cyclophilin (Cyp18).

R Golbik1, G Fischer, A R Fersht.   

Abstract

Refolding of b*C40A/C82A/P27A is comprised of several kinetically detectable folding phases. The slowest phase in refolding originates from trans-->cis isomerization of the Tyr47-Pro48 peptide bond being in cis conformation in the native state. This refolding phase can be accelerated by the peptidyl-prolyl cis/trans isomerase human cytosolic cyclophilin (Cyp18) with a kcat/K(M) of 254,000 M(-1) s(-1). The fast refolding phase is not influenced by the enzyme.

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Year:  1999        PMID： 10422840      PMCID： PMC2144385          DOI： 10.1110/ps.8.7.1505

Source DB:  PubMed          Journal:  Protein Sci        ISSN： 0961-8368            Impact factor:   6.725


  54 in total

1.  Calculation of protein extinction coefficients from amino acid sequence data.

Authors:  S C Gill; P H von Hippel
Journal:  Anal Biochem       Date:  1989-11-01       Impact factor: 3.365

2.  Barnase and barstar. Expression of its cloned inhibitor permits expression of a cloned ribonuclease.

Authors:  R W Hartley
Journal:  J Mol Biol       Date:  1988-08-20       Impact factor: 5.469

3.  Refolding behavior of a kinetic intermediate observed in the low pH unfolding of ribonuclease A.

Authors:  P J Hagerman; F X Schmid; R L Baldwin
Journal:  Biochemistry       Date:  1979-01-23       Impact factor: 3.162

4.  Unfolding free energy changes determined by the linear extrapolation method. 2. Incorporation of delta G degrees N-U values in a thermodynamic cycle.

Authors:  D W Bolen; M M Santoro
Journal:  Biochemistry       Date:  1988-10-18       Impact factor: 3.162

5.  Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants.

Authors:  M M Santoro; D W Bolen
Journal:  Biochemistry       Date:  1988-10-18       Impact factor: 3.162

6.  Catalysis of protein folding by prolyl isomerase.

Authors:  K Lang; F X Schmid; G Fischer
Journal:  Nature       Date:  1987 Sep 17-23       Impact factor: 49.962

7.  Intramolecular assistance of cis/trans isomerization of the histidine-proline moiety.

Authors:  U Reimer; N el Mokdad; M Schutkowski; G Fischer
Journal:  Biochemistry       Date:  1997-11-11       Impact factor: 3.162

8.  Mechanism of folding of ribonuclease A. Slow refolding is a sequential reaction via structural intermediates.

Authors:  F X Schmid
Journal:  Biochemistry       Date:  1983-09-27       Impact factor: 3.162

9.  Kinetic characterization of the recombinant ribonuclease from Bacillus amyloliquefaciens (barnase) and investigation of key residues in catalysis by site-directed mutagenesis.

Authors:  D E Mossakowska; K Nyberg; A R Fersht
Journal:  Biochemistry       Date:  1989-05-02       Impact factor: 3.162

10.  [Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides].

Authors:  G Fischer; H Bang; C Mech
Journal:  Biomed Biochim Acta       Date:  1984
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  4 in total

1.  Proteins with beta-(thienopyrrolyl)alanines as alternative chromophores and pharmaceutically active amino acids.

Authors:  N Budisa; S Alefelder; J H Bae; R Golbik; C Minks; R Huber; L Moroder
Journal:  Protein Sci       Date:  2001-07       Impact factor: 6.725

2.  Effect of environmental conditions on aggregation and fibril formation of barstar.

Authors:  K Gast; A J Modler; H Damaschun; R Kröber; G Lutsch; D Zirwer; R Golbik; G Damaschun
Journal:  Eur Biophys J       Date:  2003-07-26       Impact factor: 1.733

3.  NF90-NF45 is a selective RNA chaperone that rearranges viral and cellular riboswitches: biochemical analysis of a virus host factor activity.

Authors:  Tobias Schmidt; Susann Friedrich; Ralph Peter Golbik; Sven-Erik Behrens
Journal:  Nucleic Acids Res       Date:  2017-12-01       Impact factor: 16.971

4.  Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline.

Authors:  Thomas Steiner; Petra Hess; Jae Hyun Bae; Birgit Wiltschi; Luis Moroder; Nediljko Budisa
Journal:  PLoS One       Date:  2008-02-27       Impact factor: 3.240
  4 in total

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