UNLABELLED: Our aim was to identify factors predictive of death in preterm infants in whom inhaled nitric oxide was administered in response to poor oxygenation (oxygenation index > or =15). Of the 23 (median gestational age 28 weeks, range 24-36) infants consecutively so treated, 15 died. Non-survival was commoner in infants with air leaks (12 of 12, P < 0.002) and/or a change in their oxygenation index of less than 30% in response to inhaled nitric oxide administration (P < 0.05). CONCLUSION: In preterm infants given inhaled nitric oxide because of poor oxygenation, a diagnosis of airleak and a lack of initial response are predictive of death.
UNLABELLED: Our aim was to identify factors predictive of death in preterm infants in whom inhaled nitric oxide was administered in response to poor oxygenation (oxygenation index > or =15). Of the 23 (median gestational age 28 weeks, range 24-36) infants consecutively so treated, 15 died. Non-survival was commoner in infants with air leaks (12 of 12, P < 0.002) and/or a change in their oxygenation index of less than 30% in response to inhaled nitric oxide administration (P < 0.05). CONCLUSION: In preterm infants given inhaled nitric oxide because of poor oxygenation, a diagnosis of airleak and a lack of initial response are predictive of death.
Authors: N Ambalavanan; K P Van Meurs; R Perritt; W A Carlo; R A Ehrenkranz; D K Stevenson; J A Lemons; W K Poole; R D Higgins Journal: J Perinatol Date: 2008-03-13 Impact factor: 2.521
Authors: Do Hyun Kim; June Dong Park; Han Suk Kim; So Yeon Shim; Ee Kyung Kim; Beyong Il Kim; Jung Hwan Choi; Gui Won Park Journal: J Korean Med Sci Date: 2007-08 Impact factor: 2.153