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Literature DB >> 1041215

In vitro activity of penicillins against anaerobes.

F P Tally, N V Jacobus, J G Bartlett, S L Gorbach.

Abstract

The in vitro susceptibility of 162 anaerobic isolates from clinical material were tested to pencillin G, BL-P1654, and carbenicillin. Penicillin G and BL-P1654 showed good activity against Bacteroides fragilis, but only 60% of strains were susceptible to carbenicillin at achievable blood levels (128 mug/ml).

Entities: Chemical Species

Mesh：

Substances：
Penicillins

Year: 1975 PMID： 1041215 PMCID： PMC429153 DOI： 10.1128/AAC.7.4.413

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

9 in total

1. Anaerobic infections of the female genital tract: bacteriologic and therapeutic aspects.

Authors: H Thadepalli; S L Gorbach; L Keith
Journal: Am J Obstet Gynecol Date: 1973-12-15 Impact factor: 8.661

2. The susceptibility of Bacteroides fragilis to 24 antibiotics.

Authors: J W Kislak
Journal: J Infect Dis Date: 1972-03 Impact factor: 5.226

3. Antibiotic sensitivity testing. Report of an international collaborative study.

Authors: H M Ericsson; J C Sherris
Journal: Acta Pathol Microbiol Scand B Microbiol Immunol Date: 1971

4. Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients.

Authors: G P Bodey; V Rodriguez; N Horikoshi; M Valdivieso
Journal: Transplant Proc Date: 1973-09 Impact factor: 1.066

5. Anaerobic infections. 1.

Authors: S L Gorbach; J G Bartlett
Journal: N Engl J Med Date: 1974-05-23 Impact factor: 91.245

6. Diagnostic features of clindamycin-associated pseudomembranous colitis.

Authors: F J Tedesco; R J Stanley; D H Alpers
Journal: N Engl J Med Date: 1974-04-11 Impact factor: 91.245

7. Antibiotic susceptibility testing of Bacteroides.

Authors: S J Bodner; M G Koenig; L L Treanor; J S Goodman
Journal: Antimicrob Agents Chemother Date: 1972-08 Impact factor: 5.191

8. The susceptibility of bacteroides to the penicillins and cephalothin.

Authors: G T Keusch; C J O'Connell
Journal: Am J Med Sci Date: 1966-04 Impact factor: 2.378

9. In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens.

Authors: W J Martin; M Gardner; J A Washington
Journal: Antimicrob Agents Chemother Date: 1972-02 Impact factor: 5.191

9 in total

7 in total

In vitro activity of penicillins against anaerobes.

1. Anaerobic infections of the female genital tract: bacteriologic and therapeutic aspects.

2. The susceptibility of Bacteroides fragilis to 24 antibiotics.

3. Antibiotic sensitivity testing. Report of an international collaborative study.

4. Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients.

5. Anaerobic infections. 1.

6. Diagnostic features of clindamycin-associated pseudomembranous colitis.

7. Antibiotic susceptibility testing of Bacteroides.

8. The susceptibility of bacteroides to the penicillins and cephalothin.

9. In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens.

1. Susceptibility testing of anaerobic bacteria with 100-microg carbenicillin disks.

2. Unique bactericidal action of metronidazole against Bacteroides fragilis and Clostridium perfringens.

3. Anaerobic bacteria: evaluation of disc susceptibility to four cephalosporins.

4. Susceptibility of anaerobic bacteria to 23 antimicrobial agents.

Review 5. Antimicrobial drugs used in the management of anaerobic infections in children.

6. Effect of L-cysteine on the activity of penicillin antibiotics against Clostridium difficile.

7. Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice.