Literature DB >> 10411774

Heart block following propofol in a child.

C Sochala1, D Deenen, A Ville, M J Govaerts.   

Abstract

We present the case of a nine-year-old boy afflicted with Ondine's curse, who developed complete atrioventricular heart block after a single bolus of propofol for induction of anaesthesia for strabismus surgery. Ondine's curse, the other name for congenital central hypoventilation syndrome, is characterized by a generalized disorder of autonomic function. Propofol has no effect on the normal atrioventricular conduction system in humans but it reduces sympathetic activity and can highly potentiate other vagal stimulation factors. Heart block has been documented after propofol bolus use in adults but, to our knowledge, not in children. It would appear that propofol is not a good choice for anaesthesia in congenital central hypoventilation syndrome.

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Year:  1999        PMID： 10411774     DOI： 10.1046/j.1460-9592.1999.00373.x

Source DB:  PubMed          Journal:  Paediatr Anaesth        ISSN： 1155-5645            Impact factor:   2.556


  9 in total

1.  Hemodynamic changes following the administration of propofol to facilitate endotracheal intubation during sevoflurane anesthesia.

Authors:  Elisabeth Dewhirst; Christopher Lancaster; Joseph D Tobias
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2.  Cardiac Arrest from Asystole During Endoscopic Retrograde Cholangiopancreatography: A Rare But Fatal Complication.

Authors:  Ajay Vallakati; Madhu Reddy; Mojtaba Olayee; Dhanunjaya Lakkireddy
Journal:  J Atr Fibrillation       Date:  2013-12-31

3.  Procedural sedation: A review of sedative agents, monitoring, and management of complications.

Authors:  Joseph D Tobias; Marc Leder
Journal:  Saudi J Anaesth       Date:  2011-10

4.  Unusual diagnosis of a persistent third-degree atrioventricular block during anesthesia in a "healthy" pediatric patient.

Authors:  Yasser Alsayegh; Claude Abdallah
Journal:  Saudi J Anaesth       Date:  2012-01

5.  Spinal anesthesia and postoperative epidural analgesia in a patient with congenital central hypoventilation syndrome -a case report.

Authors:  Yongjoon Choi; Sunam Lee; Jiyeon Lee; Seongwon Woo
Journal:  Korean J Anesthesiol       Date:  2018-11-14

6.  Comparing the effects of three different additional doses of propofol infusion on intubation condition and hemodynamic changes during general anesthesia under elective surgery: A randomized, placebo-controlled, double blind clinical trial.

Authors:  Mohammadreza Safavi; Azim Honarmand; Golnaz Banisadr
Journal:  Adv Biomed Res       Date:  2014-05-28

7.  Conscious sedation with dexmedetomidine for implantation of a phrenic nerve stimulator in a pediatric case of late-onset congenital central hypoventilation syndrome.

Authors:  Keiko Hirooka; Kotoe Kamata; Shiro Horisawa; Minoru Nomura; Takaomi Taira; Makoto Ozaki
Journal:  JA Clin Rep       Date:  2017-08-31

Review 8.  Guidelines for diagnosis and management of congenital central hypoventilation syndrome.

Authors:  Ha Trang; Martin Samuels; Isabella Ceccherini; Matthias Frerick; Maria Angeles Garcia-Teresa; Jochen Peters; Johannes Schoeber; Marek Migdal; Agneta Markstrom; Giancarlo Ottonello; Raffaele Piumelli; Maria Helena Estevao; Irena Senecic-Cala; Barbara Gnidovec-Strazisar; Andreas Pfleger; Raquel Porto-Abal; Miriam Katz-Salamon
Journal:  Orphanet J Rare Dis       Date:  2020-09-21       Impact factor: 4.123

9.  Propofol suppresses the His-ventricular conduction in paediatric patients.

Authors:  Mayuka Matsushima; Seishi Kimura; Atsuhiro Kitaura; Shinichi Hamasaki; Tatsushige Iwamoto; Takashi Mino; Kenichi Masui; Shinichi Nakao
Journal:  J Clin Pharm Ther       Date:  2020-10-24       Impact factor: 2.512
  9 in total

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