Literature DB >> 10409525

Surgery for aortic stenosis in severely symptomatic patients older than 80 years: experience in a single UK centre.

T Gilbert1, W Orr, A P Banning.   

Abstract

OBJECTIVE: To ascertain the surgical risk and long term outcome of patients over 80 years old undergoing aortic valve replacement (AVR).
DESIGN: Consecutive cases with respective case note audit and a telephone questionnaire.
SETTING: Single UK cardiothoracic surgical centre. PATIENTS: 103 (48 male) patients over 80 years old undergoing AVR. The median age was 82 years (80-95 years) and 95 of 103 patients were in New York Heart Association (NYHA) class III or IV. METHOD AND
RESULTS: Preoperative characteristics, operative course, cost, and outcome measures were ascertained. Mean bypass time was 56 minutes and 25 patients had simultaneous coronary artery bypass grafting. Overall mortality was 19 of 103. Univariate analysis of pertinent variables found that impaired renal function and peripheral vascular disease were significantly associated with early postoperative death. 10 of 12 patients requiring ventilation for more than 24 hours died. The 50% actuarial survival was 62 months. Late complications were uncommon with 92% of patients in NYHA class I or II at follow up.
CONCLUSIONS: AVR in patients over 80 years old has a significant risk. However, those patients who survive experience significant benefit with good long term prospects for general health and social independence.

Entities:  

Mesh:

Year:  1999        PMID: 10409525      PMCID: PMC1729117          DOI: 10.1136/hrt.82.2.138

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  13 in total

1.  Aortic valve replacement in octogenarians with aortic stenosis: a case-control study.

Authors:  M Olsson; L Granström; D Lindblom; M Rosenqvist; L Rydén
Journal:  J Am Coll Cardiol       Date:  1992-12       Impact factor: 24.094

2.  Aortic valve replacement for aortic stenosis in persons aged 80 years and over.

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Journal:  Am J Cardiol       Date:  1991-06-01       Impact factor: 2.778

Review 3.  Why angina pectoris in aortic stenosis.

Authors:  K L Gould
Journal:  Circulation       Date:  1997-02-18       Impact factor: 29.690

4.  Open-heart surgery in octogenarians.

Authors:  L H Edmunds; L W Stephenson; R N Edie; M B Ratcliffe
Journal:  N Engl J Med       Date:  1988-07-21       Impact factor: 91.245

5.  Natural history of candidates for balloon aortic valvuloplasty.

Authors:  J H O'Keefe; R E Vlietstra; K R Bailey; D R Holmes
Journal:  Mayo Clin Proc       Date:  1987-11       Impact factor: 7.616

6.  Aortic valve replacement in patients 80 years of age and older: survival and cause of death based on 1100 cases: collective results from the UK Heart Valve Registry.

Authors:  G Asimakopoulos; M B Edwards; K M Taylor
Journal:  Circulation       Date:  1997-11-18       Impact factor: 29.690

7.  Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample.

Authors:  M Lindroos; M Kupari; J Heikkilä; R Tilvis
Journal:  J Am Coll Cardiol       Date:  1993-04       Impact factor: 24.094

8.  Stroke following coronary artery bypass grafting: a ten-year study.

Authors:  T J Gardner; P J Horneffer; T A Manolio; T A Pearson; V L Gott; W A Baumgartner; A M Borkon; L Watkins; B A Reitz
Journal:  Ann Thorac Surg       Date:  1985-12       Impact factor: 4.330

9.  Valve replacement in the octogenarian.

Authors:  A C Fiore; K S Naunheim; H B Barner; D G Pennington; L R McBride; G C Kaiser; V L Willman
Journal:  Ann Thorac Surg       Date:  1989-07       Impact factor: 4.330

10.  Quality of life in octogenarians after valve replacement due to aortic stenosis. A prospective comparison with younger patients.

Authors:  M Olsson; H Janfjäll; K Orth-Gomér; A Undén; M Rosenqvist
Journal:  Eur Heart J       Date:  1996-04       Impact factor: 29.983

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  4 in total

Review 1.  Ageism in cardiology.

Authors:  A Bowling
Journal:  BMJ       Date:  1999-11-20

Review 2.  Interface between valve disease and ischaemic heart disease.

Authors:  B Iung
Journal:  Heart       Date:  2000-09       Impact factor: 5.994

3.  Importance of risk communication and decision making in cardiovascular conditions in older patients: a discussion paper.

Authors:  N Dudley
Journal:  Qual Health Care       Date:  2001-09

4.  Transcatheter versus surgical aortic valve replacement: a systematic review and meta-analysis of randomised and non-randomised trials.

Authors:  Vinayak Nagaraja; Jwalant Raval; Guy D Eslick; Andrew T L Ong
Journal:  Open Heart       Date:  2014-08-12
  4 in total

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