Literature DB >> 10402525

Parathyroid biopsy to facilitate the preservation of functional parathyroid tissue during thyroidectomy.

W I Kuhel1, J F Carew.   

Abstract

BACKGROUND: The preservation of viable parathyroid tissue, either by preserving parathyroid glands in situ with an intact blood supply or by autotransplantation, is an integral element of thyroid surgery. There is a general impression that nonviable parathyroid glands can be recognized on the basis of black or purple-black discoloration of the gland. We came to believe that this is not a reliable way to assess the viability of parathyroid glands because we observed that when we excised parathyroid glands (with the intention of reimplanting them) in situations where it was not feasible to preserve their blood supply, they did not become discolored.
METHODS: To assess the status of the parathyroid blood supply, we performed incisional biopsies of suspected parathyroid glands during 14 consecutive thyroid operations (9 hemithyroidectomies, 1 completion thyroidectomy, 4 total thyroidectomies), and observed the biopsy site for evidence of active bleeding.
RESULTS: Thirty-four of 36 possible parathyroid glands were histologically confirmed. Seventeen bled actively from the biopsy site and were preserved in situ. The other 17 were felt to be nonviable: 5 were severely discolored (black) and either no bleeding or minor venous oozing was seen when they were biopsied; 12 with normal coloration (3 were harvested prior to biopsy), did not bleed actively following an incisional biopsy. Parathyroid glands that were judged to be devascularized were autotransplanted into the sternocleidomastoid muscle.
CONCLUSIONS: The absence of discoloration is not a reliable way to determine whether the parathyroid blood supply is intact. Biopsy of the parathyroid glands during thyroid surgery facilitates the identification of devascularized parathyroid glands that can be salvaged with autotransplantation. Copyright 1999 John Wiley & Sons, Inc. Head Neck 21: 442-446, 1999.

Entities:  

Mesh:

Year:  1999        PMID: 10402525     DOI: 10.1002/(sici)1097-0347(199908)21:5<442::aid-hed10>3.0.co;2-z

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  10 in total

1.  Applicability of intraoperative parathyroid hormone assay during thyroidectomy.

Authors:  Chung Yau Lo; John M Luk; Sidney C Tam
Journal:  Ann Surg       Date:  2002-11       Impact factor: 12.969

2.  The Association of Discolored Parathyroid Glands and Hypoparathyroidism Following Total Thyroidectomy.

Authors:  Brian Hung-Hin Lang; Diane T Y Chan; Felix Che-Lok Chow; Kai Pun Wong; Rita Y K Chang
Journal:  World J Surg       Date:  2016-07       Impact factor: 3.352

Review 3.  Parathyroid transplantation in thyroid surgery.

Authors:  Marcin Barczyński; Filip Gołkowski; Ireneusz Nawrot
Journal:  Gland Surg       Date:  2017-10

Review 4.  To identify or not to identify parathyroid glands during total thyroidectomy.

Authors:  Yuk Kwan Chang; Brian H H Lang
Journal:  Gland Surg       Date:  2017-12

5.  Value of intraoperative parathyroid hormone monitoring in papillary thyroid cancer surgery: can it be used to guide the choice of operation methods?

Authors:  Jiafeng Wang; Jialei Gu; Qianbo Han; Wendong Wang; Jinbiao Shang
Journal:  Int J Clin Exp Med       Date:  2015-05-15

6.  Parathyroid gland angiography with indocyanine green fluorescence to predict parathyroid function after thyroid surgery.

Authors:  J Vidal Fortuny; V Belfontali; S M Sadowski; W Karenovics; S Guigard; F Triponez
Journal:  Br J Surg       Date:  2016-02-11       Impact factor: 6.939

7.  Randomized clinical trial of intraoperative parathyroid gland angiography with indocyanine green fluorescence predicting parathyroid function after thyroid surgery.

Authors:  J Vidal Fortuny; S M Sadowski; V Belfontali; S Guigard; A Poncet; F Ris; W Karenovics; F Triponez
Journal:  Br J Surg       Date:  2018-02-06       Impact factor: 6.939

8.  A new classification of parathyroid glands to evaluate in situ preservation or autotransplantation during thyroid surgery.

Authors:  Anping Su; Yanping Gong; Tao Wei; Rixiang Gong; Zhihui Li; Jingqiang Zhu
Journal:  Medicine (Baltimore)       Date:  2018-11       Impact factor: 1.817

9.  Postoperative Hypoparathyroidism and the Viability of the Parathyroid Glands During Thyroidectomy.

Authors:  Yong Bae Ji; Chang Myeon Song; Eui Suk Sung; Jin Hyeok Jeong; Chang Beom Lee; Kyung Tae
Journal:  Clin Exp Otorhinolaryngol       Date:  2016-08-13       Impact factor: 3.372

10.  Prospective study of clinical and laboratorial hypocalcemia after thyroid surgery.

Authors:  Rogério Aparecido Dedivitis; Elio Gilberto Pfuetzenreiter; Carlos Eduardo Molinari Nardi; Emmanuel Casotti Duque de Barbara
Journal:  Braz J Otorhinolaryngol       Date:  2010 Jan-Feb
  10 in total

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