| Literature DB >> 10399855 |
Abstract
This review article underlines the importance of gas chromatography-mass spectrometry (GC-MS) for determination of steroids in man. The use of steroids labelled with stable isotopes as internal standard and subsequent analysis by GC-MS yields up to now the only reliable measurement of steroids in serum. Isotope dilution GC-MS is the reference method for evaluation of routine analysis of serum steroid hormones. GC-MS is an important tool for detection of steroid hormone doping and combined with a combustion furnace and an isotope ratio mass spectrometer the misuse of testosterone by athletes can be discovered. Finally the so called urinary steroid profile by GC and GC-MS is the method of choice for detection of steroid metabolites in health and disease.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10399855 DOI： 10.1016/s0021-9673(99)00153-3
Source DB: PubMed Journal: J Chromatogr A ISSN： 0021-9673 Impact factor: 4.759