Literature DB >> 10395566

V(D)J recombination: on the cutting edge.

M A Oettinger1.   

Abstract

The vertebrate immune system has evolved an elegant mechanism for generating an enormous diversity in antigen receptor binding specificity from a limited amount of genetic information. Recent advances are rapidly increasing our understanding of this unusual site-specific DNA rearrangement that assembles the antigen receptor genes during lymphoid development.

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Year:  1999        PMID： 10395566     DOI： 10.1016/S0955-0674(99)80044-1

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  20 in total

Review 1.  The RAG proteins in V(D)J recombination: more than just a nuclease.

Authors:  M J Sadofsky
Journal:  Nucleic Acids Res       Date:  2001-04-01       Impact factor: 16.971

2.  Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase.

Authors:  D R Kim; Y Dai; C L Mundy; W Yang; M A Oettinger
Journal:  Genes Dev       Date:  1999-12-01       Impact factor: 11.361

3.  Mechanism for specificity by HMG-1 in enhanceosome assembly.

Authors:  K B Ellwood; Y M Yen; R C Johnson; M Carey
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

Review 4.  Regulation of antigen receptor gene assembly in lymphocytes.

Authors:  E M Oltz
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829

5.  Assembly of the RAG1/RAG2 synaptic complex.

Authors:  Cynthia L Mundy; Nadja Patenge; Adam G W Matthews; Marjorie A Oettinger
Journal:  Mol Cell Biol       Date:  2002-01       Impact factor: 4.272

6.  Site-specific recombination by the DDE family member mobile element IS30 transposase.

Authors:  János Kiss; Mónika Szabó; Ferenc Olasz
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-09       Impact factor: 11.205

7.  Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.

Authors:  Michael L Sikes; Amber Meade; Rajkamal Tripathi; Michael S Krangel; Eugene M Oltz
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-26       Impact factor: 11.205

8.  Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.

Authors:  R K Tripathi; N Mathieu; S Spicuglia; D Payet; C Verthuy; G Bouvier; D Depetris; M G Mattei; W M HempeL; P Ferrier
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

9.  Integrated signaling in developing lymphocytes: the role of DNA damage responses.

Authors:  Jeffrey J Bednarski; Barry P Sleckman
Journal:  Cell Cycle       Date:  2012-10-03       Impact factor: 4.534

10.  Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRbeta locus.

Authors:  Bernard Khor; Grace K Mahowald; Katrina Khor; Barry P Sleckman
Journal:  Mol Immunol       Date:  2008-12-13       Impact factor: 4.407
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